Varaico: Literature-Extracted Genetic Variants

Gene:APOC3
Variant:p.D65N
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APOC3

NM_000040.3:p.D65N

Associated Papers

Compact RNA editors with natural miniature Cas13j nucleases.

Li G et al.

Nature Chemical Biology, 2025

A novel base editor SpRY-ABE8eF148A mediates efficient A-to-G base editing with a reduced off-target effect.

Li G et al.

Molecular Therapy. Nucleic Acids, 2023

Ethnic differences in ApoC-III concentration and the risk of cardiovascular disease: No evidence for the cardioprotective role of rare/loss of function APOC3 variants in non-Europeans.

Rout M et al.

American Heart Journal Plus : Cardiology Research and Practice, 2022

APOC3 genetic variation, serum triglycerides, and risk of coronary artery disease in Asian Indians, Europeans, and other ethnic groups.

Goyal S et al.

Lipids in Health and Disease, 2021

Guidelines for Large-Scale Sequence-Based Complex Trait Association Studies: Lessons Learned from the NHLBI Exome Sequencing Project.

Auer PL et al.

American Journal of Human Genetics, 2016

Loss-of-function mutations in APOC3, triglycerides, and coronary disease.

Crosby J et al.

The New England Journal of Medicine, 2014

Loss-of-function mutations in APOC3 and risk of ischemic vascular disease.

Jørgensen AB et al.

The New England Journal of Medicine, 2014

24941082 (PubMed )
Supplement: nejmoa1308027_appendix.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."