Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.W38S
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APOE

NM_000041.4:p.W38S

Associated Papers

Alzheimer Disease Associated Loci: APOE Single Nucleotide Polymorphisms in Marmara Region.

Ismail AB et al.

Biomedicines, 2024

APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample.

Choi KY et al.

Journal of Clinical Medicine, 2019

The Association of Polymorphisms in Circadian Clock and Lipid Metabolism Genes With 2nd Trimester Lipid Levels and Preterm Birth.

Kovac U et al.

Frontiers in Genetics, 2019

31249592 (PubMed )
Supplement: Presentation_1.pdf

The algorithm for Alzheimer risk assessment based on APOE promoter polymorphisms.

Limon-Sztencel A et al.

Alzheimer's Research & Therapy, 2016

Role of apolipoprotein E polymorphism as a prognostic marker in traumatic brain injury and neurodegenerative disease: a critical review.

Maiti TK et al.

Neurosurgical Focus, 2015

The rs1803274 polymorphism of the BCHE gene is associated with an increased risk of coronary in-stent restenosis.

Pleva L et al.

Bmc Cardiovascular Disorders, 2015

Can APOE and MTHFR polymorphisms have an influence on the severity of cardiovascular manifestations in Italian Pseudoxanthoma elasticum affected patients?

Boraldi F et al.

Molecular Genetics and Metabolism Reports, 2014

27896127 (PubMed )
Supplement: mmc1.docx

Apolipoprotein E genotype: the innocent bystander or active bridge between metabolic syndrome and cognitive impairment?

Frisardi V

Journal of Alzheimer's Disease : Jad, 2012

A functional mutation at position -155 in porcine APOE promoter affects gene expression.

Li S et al.

Bmc Genetics, 2011

Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake - the Cardiovascular Risk in Young Finns study.

Tolonen S et al.

Bone, 2011

The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks.

Komurcu-Bayrak E et al.

Metabolism: Clinical and Experimental, 2011

APOE genotype-function relationship: evidence of -491 A/T promoter polymorphism modifying transcription control but not type 2 diabetes risk.

Geng H et al.

Plos One, 2011

Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis.

Viiri LE et al.

Circulation. Cardiovascular Genetics, 2008

Associations of apolipoprotein E gene with ischemic stroke and intracranial atherosclerosis.

Abboud S et al.

European Journal of Human Genetics : Ejhg, 2008

Genetic variation and atherosclerosis.

Biros E et al.

Current Genomics, 2008

Association and linkage disequilibrium analyses of APOE polymorphisms in atherosclerosis.

Artieda M et al.

Disease Markers, 2008

Association of the apolipoprotein E gene, its promoter polymorphisms and haplotypes with depressive symptoms. The Cardiovascular Risk in Young Finns Study.

Elovainio M et al.

Neuropsychobiology, 2008

Genetic determinants of plasma lipoproteins.

Pollex RL et al.

Nature Clinical Practice. Cardiovascular Medicine, 2007

Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene and the rate of cognitive decline in Alzheimer's disease.

Belbin O et al.

Human Molecular Genetics, 2007

Relations of APOE promoter polymorphisms to LDL cholesterol and markers of subclinical atherosclerosis in young adults.

Viiri LE et al.

Journal of Lipid Research, 2006

Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Study.

North KE et al.

Journal of Lipid Research, 2006

The association of the apolipoprotein E gene promoter polymorphisms and haplotypes with serum lipid and lipoprotein concentrations.

Viiri LE et al.

Atherosclerosis, 2005

Comprehensive association analysis of APOE regulatory region polymorphisms in Alzheimer disease.

Nicodemus KK et al.

Neurogenetics, 2004

Apolipoprotein E gene polymorphisms and thrombosis and restenosis after coronary artery stenting.

Koch W et al.

Journal of Lipid Research, 2004

Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes.

Bray NJ et al.

Human Molecular Genetics, 2004

The allelic modulation of apolipoprotein E expression by oestrogen: potential relevance for Alzheimer's disease.

Lambert JC et al.

Journal of Medical Genetics, 2004

Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription.

Laws SM et al.

Journal of Neurochemistry, 2003

TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E.

Koch W et al.

Clinical Chemistry and Laboratory Medicine, 2002

Association of APOE epsilon2/epsilon3/epsilon4 and promoter gene variants with dementia but not cardiovascular mortality in old age.

Heijmans BT et al.

American Journal of Medical Genetics, 2002

Apolipoprotein E gene promoter polymorphisms in Alzheimer's disease.

Bullido MJ et al.

Microscopy Research and Technique, 2000

Allelic polymorphisms in the transcriptional regulatory region of apolipoprotein E gene.

Artiga MJ et al.

Febs Letters, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."