Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.S112P
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APOE

NM_000041.4:p.S112P

Associated Papers

Serum HDL-cholesterol is associated with the clinical-biological profile of early-stage Parkinson's disease patients independently of APOE.

Mascioli D et al.

Neurobiology of Aging, 2025

Exploring the effect of APOE ε4 on biomarkers of neurodegeneration in Alzheimer's disease.

Agnello L et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2024

Analysis of endothelial gene polymorphisms in Spanish patients with vascular dementia and Alzheimer´s disease.

Manso-Calderón R et al.

Scientific Reports, 2023

Increase of serum uric acid levels associated with APOE ε2 haplotype: a clinico-genetic investigation and in vivo approach.

Ogura M et al.

Human Cell, 2021

Trace elements and APOE polymorphisms in pregnant women and their new-borns.

Trdin A et al.

Environment International, 2020

Apolipoprotein E Gene Polymorphism, Glycated Hemoglobin, and Peripheral Arterial Disease Risk in Chinese Type 2 Diabetic Patients.

Hu Y et al.

Disease Markers, 2020

Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins.

Arrigoni E et al.

International Journal of Molecular Sciences, 2017

TOMM40 and APOE Gene Expression and Cognitive Decline in Japanese Alzheimer's Disease Subjects.

Mise A et al.

Journal of Alzheimer's Disease : Jad, 2017

Influence of APOE Gene Polymorphism on Interindividual and Interethnic Warfarin Dosage Requirement: A Systematic Review and Meta-Analysis.

Yu WY et al.

Cardiovascular Therapeutics, 2016

The rs1803274 polymorphism of the BCHE gene is associated with an increased risk of coronary in-stent restenosis.

Pleva L et al.

Bmc Cardiovascular Disorders, 2015

Association of ApoE gene with type 2 diabetic nephropathy in a Chinese population: a meta-analysis of case-control studies.

Zhang C et al.

Annales D'endocrinologie, 2015

The cis-regulatory effect of an Alzheimer's disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes.

Linnertz C et al.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2014

Genetic markers associated to dyslipidemia in HIV-infected individuals on HAART.

Lazzaretti RK et al.

Thescientificworldjournal, 2013

Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease.

Soares HD et al.

Archives of Neurology, 2012

Apolipoprotein E ε2 and functional decline in amnestic mild cognitive impairment and Alzheimer disease.

Bonner-Jackson A et al.

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry, 2012

Characterization of the poly-T variant in the TOMM40 gene in diverse populations.

Linnertz C et al.

Plos One, 2012

Potential utility of soluble p3-alcadein α plasma levels as a biomarker for sporadic Alzheimer's disease.

Kamogawa K et al.

Journal of Alzheimer's Disease : Jad, 2012

The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks.

Komurcu-Bayrak E et al.

Metabolism: Clinical and Experimental, 2011

COMT Val158Met Genotype and Individual Differences in Executive Function in Healthy Adults.

Wishart HA et al.

Journal of the International Neuropsychological Society : Jins, 2011

Effect of central obesity, low high-density lipoprotein cholesterol and C-reactive protein polymorphisms on C-reactive protein levels during treatment with Rosuvastatin (10 mg Daily).

Hu M et al.

The American Journal of Cardiology, 2010

Apolipoprotein A-I positively associated with diabetes in women independently of apolipoprotein E genotype and apolipoprotein B levels.

Onat A et al.

Nutrition (burbank, Los Angeles County, Calif.), 2010

Temporal lobe functional activity and connectivity in young adult APOE varepsilon4 carriers.

Dennis NA et al.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2010

Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down syndrome.

Prasher VP et al.

International Journal of Geriatric Psychiatry, 2008

Robust association of the APOE epsilon4 allele with premature myocardial infarction especially in patients without hypercholesterolaemia: the Aachen study.

Schmitz F et al.

European Journal of Clinical Investigation, 2007

Apolipoprotein E genotype affects the response to lipid-lowering therapy in Chinese patients with type 2 diabetes mellitus.

Tavintharan S et al.

Diabetes, Obesity & Metabolism, 2007

New insight into the association of apolipoprotein E genetic variants with carotid plaques and intima-media thickness.

Debette S et al.

Stroke, 2006

Warfarin dose related to apolipoprotein E (APOE) genotype.

Kohnke H et al.

European Journal of Clinical Pharmacology, 2005

Apolipoprotein E gene polymorphisms and thrombosis and restenosis after coronary artery stenting.

Koch W et al.

Journal of Lipid Research, 2004

Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes.

Bray NJ et al.

Human Molecular Genetics, 2004

TaqMan systems for genotyping of disease-related polymorphisms present in the gene encoding apolipoprotein E.

Koch W et al.

Clinical Chemistry and Laboratory Medicine, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."