Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.L159R
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APOE

NM_000041.4:p.L159R

Associated Papers

Structural Analysis of Missense Mutations on the Stability of APOE3 and APOE4.

Anthony M et al.

Genes, 2025

41465183 (PubMed )
Supplement: genes-16-01509-s001.zip › Supplementary_Table_S1_APOE3_1NFN_.xlsx › Sheet1

Natural human apoA-I mutations L141RPisa and L159RFIN alter HDL structure and functionality and promote atherosclerosis development in mice.

Tiniakou I et al.

Atherosclerosis, 2015

HDL biogenesis, remodeling, and catabolism.

Zannis VI et al.

Handbook of Experimental Pharmacology, 2015

Molecular etiology of a dominant form of type III hyperlipoproteinemia caused by R142C substitution in apoE4.

Vezeridis AM et al.

Journal of Lipid Research, 2011

Discrete roles of apoA-I and apoE in the biogenesis of HDL species: lessons learned from gene transfer studies in different mouse models.

Zannis VI et al.

Annals of Medicine, 2008

Ratio determination of plasma wild-type and L159R apoA-I using mass spectrometry: tools for studying apoA-IFin.

Owen JS et al.

Journal of Lipid Research, 2007

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