Associated Papers
Integrative bioinformatics analysis of APOE variants in Alzheimer's disease and clinical therapeutics.
Srivastava K et al.
Journal of Biomolecular Structure & Dynamics, 2025
Mapping the APOE structurally on missense variants in elderly Brazilians.
de Lima Pizzico F et al.
Journal of Biomolecular Structure & Dynamics, 2025
Molecular dynamics of select missense mutations of Apolipoprotein E and their implications in Hyperlipoproteinemia type III.
Thakur S et al.
Biochemistry and Biophysics Reports, 2025
Biobank-scale genetic characterization of Alzheimer's disease and related dementias across diverse ancestries.
Khani M et al.
Nature Communications, 2025
Genetic Variants Affect Distinct Metabolic Pathways in Pediatric Multisystem Inflammatory Syndrome and Severe COVID-19.
Urbanski AH et al.
Journal of Medical Virology, 2025
Association of rare APOE missense variants with Alzheimer's disease in the Japanese population.
Miyashita A et al.
Journal of Alzheimer's Disease : Jad, 2025
Impact of Apolipoprotein E Variants: A Review of Naturally Occurring Variants and Clinical Features.
Matsunaga A et al.
Journal of Atherosclerosis and Thrombosis, 2025
The diagnostic yield of exome sequencing in liver diseases from a curated gene panel.
Kong XF et al.
Scientific Reports, 2023
Additive Effect of APOE Rare Variants on the Phenotype of Familial Hypercholesterolemia.
Marmontel O et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2023
Contribution of APOE Genetic Variants to Dyslipidemia.
Bea AM et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2023
Apolipoprotein E (APOE) Haplotypes in Healthy Subjects from Worldwide Macroareas: A Population Genetics Perspective for Cardiovascular Disease, Neurodegeneration, and Dementia.
Abondio P et al.
Current Issues in Molecular Biology, 2023
Genetics of Alzheimer's disease: an East Asian perspective.
Miyashita A et al.
Journal of Human Genetics, 2023
Brain radiotoxicity-related 15CAcBRT gene expression signature predicts survival prognosis of glioblastoma patients.
Reyes-González J et al.
Neuro-oncology, 2023
Genetic and molecular architecture of familial hypercholesterolemia.
Abifadel M et al.
Journal of Internal Medicine, 2023
Orthogonal analysis of variants in APOE gene using in-silico approaches reveals novel disrupting variants.
Li C et al.
Frontiers in Bioinformatics, 2023
Establishing the relationship between familial dysbetalipoproteinemia and genetic variants in the APOE gene.
Heidemann BE et al.
Clinical Genetics, 2022
APOE Molecular Spectrum in a French Cohort with Primary Dyslipidemia.
Abou Khalil Y et al.
International Journal of Molecular Sciences, 2022
High-depth African genomes inform human migration and health.
Choudhury A et al.
Nature, 2020
The Genetics of Alzheimer's Disease in the Chinese Population.
Gan CL et al.
International Journal of Molecular Sciences, 2020
The familial hypercholesterolaemia phenotype: Monogenic familial hypercholesterolaemia, polygenic hypercholesterolaemia and other causes.
Mariano C et al.
Clinical Genetics, 2020
Reinterpretation of common pathogenic variants in ClinVar revealed a high proportion of downgrades.
Xiang J et al.
Scientific Reports, 2020
Apolipoprotein E-C1-C4-C2 gene cluster region and inter-individual variation in plasma lipoprotein levels: a comprehensive genetic association study in two ethnic groups.
Pirim D et al.
Plos One, 2019
Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk.
Zhou Y et al.
Journal of Lipid Research, 2018
Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.
Lu X et al.
Nature Genetics, 2017
In silico analyses of deleterious missense SNPs of human apolipoprotein E3.
Pires AS et al.
Scientific Reports, 2017
Variable phenotypic expression of nonsense mutation p.Thr5* in the APOE gene.
Leren TP et al.
Molecular Genetics and Metabolism Reports, 2016
Global molecular analysis and APOE mutations in a cohort of autosomal dominant hypercholesterolemia patients in France.
Wintjens R et al.
Journal of Lipid Research, 2016
Clinical proteome informatics workbench detects pathogenic mutations in hereditary amyloidoses.
Dasari S et al.
Journal of Proteome Research, 2014
Genome-wide family-based linkage analysis of exome chip variants and cardiometabolic risk.
Hellwege JN et al.
Genetic Epidemiology, 2014
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.
Peloso GM et al.
American Journal of Human Genetics, 2014
Comprehensive evaluation of the association of APOE genetic variation with plasma lipoprotein traits in U.S. whites and African blacks.
Radwan ZH et al.
Plos One, 2014
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained.
Wu Y et al.
Plos Genetics, 2013
Screening and Evaluation of Deleterious SNPs in APOE Gene of Alzheimer's Disease.
Masoodi TA et al.
Neurology Research International, 2012