Associated Papers
A case-control association study of APOE promoter region variants with glaucoma in North Indian population.
Passan S et al.
Human Immunology, 2025
Lack of association between common polymorphisms associated with successful aging and longevity in the population of Sardinian Blue Zone.
Errigo A et al.
Scientific Reports, 2024
Association of Gene Polymorphisms with Normal Tension Glaucoma: A Systematic Review and Meta-Analysis.
Pan L et al.
Genes, 2024
Maternally inherited diabetes and deafness coexists with lipoprotein lipase gene mutation-associated severe hyperlipidemia that was resistant to fenofibrate and atorvastatin, but sensitive to bezafibrate: A case report.
Zhang X et al.
Journal of Diabetes Investigation, 2022
Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by TOMM40-APOE variants in men.
Kulminski AM et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2021
APOE and dementia - resequencing and genotyping in 105,597 individuals.
Rasmussen KL et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2020
Role of Genetic Variations in the Hepatic Handling of Drugs.
Marin JJG et al.
International Journal of Molecular Sciences, 2020
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample.
Choi KY et al.
Journal of Clinical Medicine, 2019
The Contribution of Genetic Factors to Cognitive Impairment and Dementia: Apolipoprotein E Gene, Gene Interactions, and Polygenic Risk.
Fan J et al.
International Journal of Molecular Sciences, 2019
Vitamin E Metabolic Effects and Genetic Variants: A Challenge for Precision Nutrition in Obesity and Associated Disturbances.
Galmés S et al.
Nutrients, 2018
Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene as risk factors for Alzheimer's disease.
Bratosiewicz-Wasik J et al.
Neuroscience Letters, 2018
Brain APOE expression quantitative trait loci-based association study identified one susceptibility locus for Alzheimer's disease by interacting with APOE ε4.
Zhang A et al.
Scientific Reports, 2018
APOE gene and neuropsychiatric disorders and endophenotypes: A comprehensive review.
Forero DA et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2018
Genes associated with Type 2 Diabetes and vascular complications.
Montesanto A et al.
Aging, 2018
Genetic variation associated with the occurrence and progression of neurological disorders.
Little J et al.
Neurotoxicology, 2017
Association between polymorphisms in the promoter region of the apolipoprotein E (APOE) gene and Alzheimer's disease: A meta-analysis.
Xiao H et al.
Excli Journal, 2017
Plasma levels of apolipoprotein E, APOE genotype and risk of dementia and ischemic heart disease: A review.
Rasmussen KL
Atherosclerosis, 2016
The algorithm for Alzheimer risk assessment based on APOE promoter polymorphisms.
Limon-Sztencel A et al.
Alzheimer's Research & Therapy, 2016
Role of apolipoprotein E polymorphism as a prognostic marker in traumatic brain injury and neurodegenerative disease: a critical review.
Maiti TK et al.
Neurosurgical Focus, 2015
Neurodegenerative Genes Polymorphisms of the -491A/T APOE, the -877T/C APP and the Risk of Primary Open-angle Glaucoma in the Polish Population.
Nowak A et al.
Ophthalmic Genetics, 2015
The APOE promoter polymorphism is associated with rebleeding after spontaneous SAH in a Chinese population.
Yin C et al.
Gene, 2015
Plasma levels of apolipoprotein E and risk of dementia in the general population.
Rasmussen KL et al.
Annals of Neurology, 2015
Analysis of the expression and polymorphism of APOE, HSP, BDNF, and GRIN2B genes associated with the neurodegeneration process in the pathogenesis of primary open angle glaucoma.
Nowak A et al.
Biomed Research International, 2015
Polymorphisms of +2836 G>A in the apoE gene are strongly associated with the susceptibility to essential hypertension in the Chinese Hui population.
Yang Y et al.
Genetics and Molecular Research : Gmr, 2014
Association between Alzheimer disease and the -491T allele of regulatory region polymorphism of Apolipoprotein E in a Tunisian population.
Achouri-Rassas A et al.
Neurochemical Research, 2014
Association between ε2/3/4, promoter polymorphism (-491A/T, -427T/C, and -219T/G) at the apolipoprotein E gene, and mental retardation in children from an iodine deficiency area, China.
Li J et al.
Biomed Research International, 2014
Association of apolipoprotein E-219T>G promoter polymorphism with primary open angle glaucoma in Turkish population.
Saglar E et al.
International Journal of Ophthalmology, 2014
Transcriptional regulation and its misregulation in Alzheimer's disease.
Chen XF et al.
Molecular Brain, 2013
Identification of a functional apolipoprotein E promoter polymorphism regulating plasma apolipoprotein E concentration.
Mannila MN et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2013
APOE -491 T allele may reduce the risk of atherosclerotic lesions among middle-aged women.
Bañares VG et al.
Molecular and Cellular Biochemistry, 2012
Apolipoprotein E genotype: the innocent bystander or active bridge between metabolic syndrome and cognitive impairment?
Frisardi V
Journal of Alzheimer's Disease : Jad, 2012
Gene expression endophenotypes: a novel approach for gene discovery in Alzheimer's disease.
Ertekin-Taner N
Molecular Neurodegeneration, 2011
A functional mutation at position -155 in porcine APOE promoter affects gene expression.
Li S et al.
Bmc Genetics, 2011
Myocilin mt.1 gene promoter single nucleotide polymorphism (-1000C>G) in Brazilian patients with primary open angle glaucoma.
Kasahara N et al.
Ophthalmic Genetics, 2011
Clinical implications of pharmacogenetic variation on the effects of statins.
Maggo SD et al.
Drug Safety, 2011
The neurobiology of APOE in schizophrenia and mood disorders.
Gibbons AS et al.
Frontiers in Bioscience (landmark Edition), 2011
APOE genotype-function relationship: evidence of -491 A/T promoter polymorphism modifying transcription control but not type 2 diabetes risk.
Geng H et al.
Plos One, 2011
Integrated role of two apoliprotein E polymorphisms on apolipoprotein B levels and coronary artery disease in a biethnic population.
Ozturk Z et al.
Metabolic Syndrome and Related Disorders, 2010
Association of promoter polymorphism of apolipoprotein E gene with cerebral vasospasm after spontaneous SAH.
Wu HT et al.
Brain Research, 2010
Association of apolipoprotein E polymorphisms with temporal lobe epilepsy in a Chinese Han population.
Fu YH et al.
Epilepsy Research, 2010
Association between an intronic apolipoprotein E polymorphism and bone mineral density in Singaporean Chinese females.
Tong TY et al.
Bone, 2010
The APOE-491 A/T promoter polymorphism effect on cognitive profile of Alzheimer's patients.
Valenza A et al.
Neuroscience Letters, 2010
Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions.
Maloney B et al.
American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2010
Apolipoprotein E promoter polymorphisms and risk of Alzheimer's disease: evidence from meta-analysis.
Xin XY et al.
Journal of Alzheimer's Disease : Jad, 2010
Impact of ACE and ApoE polymorphisms on myocardial perfusion: correlation with myocardial single photon emission computed tomographic imaging.
Georgoulias P et al.
Journal of Human Genetics, 2009
Parental history of Alzheimer disease associated with lower plasma apolipoprotein E levels.
van Vliet P et al.
Neurology, 2009
The complex interaction between APOE promoter and AD: an Italian case-control study.
Bizzarro A et al.
European Journal of Human Genetics : Ejhg, 2009
Age-related macular degeneration and functional promoter and coding variants of the apolipoprotein E gene.
Fritsche LG et al.
Human Mutation, 2009
The role of the -427T/C apolipoprotein E promoter polymorphism in the pathogenesis of Alzheimer's disease, vascular dementia and mixed dementia.
Trebunová M et al.
Journal of Neural Transmission (vienna, Austria : 1996), 2009