Varaico: Literature-Extracted Genetic Variants

Gene:APOE
Variant:p.L286V
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APOE

NM_000041.4:p.L286V

Associated Papers

Adenylate kinase 5, a novel genetic risk factor for Alzheimer's disease, regulates microglial inflammatory activation.

Seong WJ et al.

Molecular Brain, 2025

Increased KIF11/kinesin-5 expression offsets Alzheimer Aβ-mediated toxicity and cognitive dysfunction.

Lucero EM et al.

Iscience, 2022

White matter aging drives microglial diversity.

Safaiyan S et al.

Neuron, 2021

APOE4 Promotes Tonic-Clonic Seizures, an Effect Modified by Familial Alzheimer's Disease Mutations.

Lamoureux L et al.

Frontiers in Cell and Developmental Biology, 2021

Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine.

Neuner SM et al.

Neuron, 2019

Clinical phenotypic heterogeneity of Alzheimer's disease associated with mutations of the presenilin-1 gene.

Larner AJ et al.

Journal of Neurology, 2006

Genetic markers in the diagnosis of Alzheimer's disease.

Rogaeva E et al.

Journal of Alzheimer's Disease : Jad, 2001

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

Mehta ND et al.

Annals of Neurology, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."