Associated Papers
Apolipoprotein L1 (APOL1): Consideration of Molecular Evolution, Interaction with APOL3, and Impact of Splice Isoforms Advances Understanding of Cellular and Molecular Mechanisms of Cell Injury.
Khalaila R et al.
Cells, 2025
The APOL1 p.N264K variant is co-inherited with the G2 kidney disease risk variant through a proximity recombination event.
Simeone CA et al.
G3 (bethesda, Md.), 2025
39658338 (PubMed )
Supplement: jkae290_supplementary_data.zip › Table_S1_G3-2024-405425.xlsx › TableS1
Protein-truncating variant in APOL3 increases chronic kidney disease risk in epistasis with APOL1 risk alleles.
Zhang DY et al.
Jci Insight, 2024
39163132 (PubMed )
Supplement: jciinsight-9-181238-s145.xlsx › Supp._Table_1
Cation channel conductance and pH gating of the innate immunity factor APOL1 are governed by pore-lining residues within the C-terminal domain.
Schaub C et al.
The Journal of Biological Chemistry, 2020
G1 is the major APOL1 risk allele for hypertension-attributed nephropathy in Central Africa.
Sumaili EK et al.
Clinical Kidney Journal, 2019
Sequencing rare and common APOL1 coding variants to determine kidney disease risk.
Limou S et al.
Kidney International, 2015
Identifying Darwinian selection acting on different human APOL1 variants among diverse African populations.
Ko WY et al.
American Journal of Human Genetics, 2013
Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease.
Hu CA et al.
Febs Letters, 2012
Advances in our understanding of the pathogenesis of HIV-1 associated nephropathy in children.
Ray PE et al.
Future Virology, 2011
ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death.
Zhaorigetu S et al.
Autophagy, 2008
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