Associated Papers
Hereditary Haemorrhagic Cerebrovascular Disease: Implications for Clinical Management.
Hou W et al.
Annals of Neurosciences, 2026
Plasma levels of an N-terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease.
Schultz SA et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2026
Aquaporin-4 and caveolin-1 as mediators of fibrinogen-driven cerebrovascular pathology in cerebral amyloid angiopathy.
Singh V et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2026
Lysosomal protease-mediated APP degradation is pH-dependent, mutation-sensitive, and facilitates tau proteolysis.
Ackley C et al.
Molecular Neurodegeneration Advances, 2026
Meningeal vascular Aβ deposition associates with cerebral hypoperfusion and compensatory collateral remodeling.
Kaloss AM et al.
Alzheimer's Research & Therapy, 2025
Protein aggregation in neurodegenerative diseases.
Wang J et al.
Chinese Medical Journal, 2025
Cryo-EM studies of amyloid-β fibrils from human and murine brains carrying the Uppsala APP mutation (Δ690-695).
Zielinski M et al.
Acta Neuropathologica Communications, 2025
Biobank-scale genetic characterization of Alzheimer's disease and related dementias across diverse ancestries.
Khani M et al.
Nature Communications, 2025
Aquaporin-4 and Caveolin-1 as Mediators of Fibrinogen-Driven Cerebrovascular Pathology in Cerebral Amyloid Angiopathy.
Singh V et al.
Biorxiv : the Preprint Server for Biology, 2025
Cytokine-induced reprogramming of human macrophages toward Alzheimer's disease-relevant molecular and cellular phenotypes in vitro.
Podleśny-Drabiniok A et al.
Cell Reports, 2025
Lysosomal Protease-Mediated APP Degradation is pH-Dependent, Mutation-Sensitive, and Facilitates Tau Proteolysis.
Ackley C et al.
Research Square, 2025
The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset.
Liu H et al.
Brain : a Journal of Neurology, 2025
Tg-SwDI transgenic mice: A suitable model for Alzheimer's disease and cerebral amyloid angiopathy basic research and preclinical studies.
Rodriguez-Lopez A et al.
Experimental Neurology, 2025
Mitochondrial dynamics and bioenergetics in Alzheimer's induced pluripotent stem cell-derived neurons.
MacMullen C et al.
Brain : a Journal of Neurology, 2025
Cerebral proteome adaptations to amyloid angiopathy are prevented by carbonic anhydrase inhibitors.
Carlsen J et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2025
Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation.
Castranio EL et al.
Biorxiv : the Preprint Server for Biology, 2025
Retinal and Optic Nerve Lesions Correspond to Amyloid in Autosomal Dominant Alzheimer's Disease.
Kashani AH et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Genetics of intracerebral hemorrhage.
Kimball TN et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, 2025
Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer's disease.
Wu Y et al.
Frontiers in Aging Neuroscience, 2025
Biobank-scale characterization of Alzheimer's disease and related dementias identifies potential disease-causing variants, risk factors, and genetic modifiers across diverse ancestries.
Khani M et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease.
Sewell KR et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2024
Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients.
Vervuurt M et al.
Acta Neuropathologica Communications, 2024
Molecular neuroimaging in dominantly inherited versus sporadic early-onset Alzheimer's disease.
Iaccarino L et al.
Brain Communications, 2024
Cerebral Proteomic Changes in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 With Cortical Microhemorrhages and Cognitive Impairments.
Schrader JM et al.
Neuroscience Insights, 2024
T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease.
Rahmani F et al.
Human Brain Mapping, 2023
Clinical considerations in early-onset cerebral amyloid angiopathy.
Banerjee G et al.
Brain : a Journal of Neurology, 2023
Interaction of Proteins Involved in Neuronal Proteinopathies.
Kulichikhin KY et al.
Life (basel, Switzerland), 2023
Genetic repair of a human induced pluripotent cell line from patient with Dutch-type cerebral amyloid angiopathy.
Nahon DM et al.
Stem Cell Research, 2023
Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN).
McKay NS et al.
Nature Neuroscience, 2023
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition.
Chatterjee P et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2023
Plasma amyloid beta 42 is a biomarker for patients with hereditary, but not sporadic, cerebral amyloid angiopathy.
de Kort AM et al.
Alzheimer's Research & Therapy, 2023
Cryo-EM structures of amyloid-β filaments with the Arctic mutation (E22G) from human and mouse brains.
Yang Y et al.
Acta Neuropathologica, 2023
Amyloid precursor protein 𝛽CTF accumulates in synapses in sporadic and genetic forms of Alzheimer's disease.
Ferrer-Raventós P et al.
Neuropathology and Applied Neurobiology, 2023
Decreased ratios of matrix metalloproteinases to tissue-type inhibitors in cerebrospinal fluid in sporadic and hereditary cerebral amyloid angiopathy.
Vervuurt M et al.
Alzheimer's Research & Therapy, 2023
Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study.
Boerwinkle AH et al.
The Lancet. Neurology, 2023
An Alternative View of Familial Alzheimer's Disease Genetics.
Lardelli M
Journal of Alzheimer's Disease : Jad, 2023
Hippocampal glial inflammatory markers are differentially altered in a novel mouse model of perimenopausal cerebral amyloid angiopathy.
Platholi J et al.
Frontiers in Aging Neuroscience, 2023
Genetics of migraine: Delineation of contemporary understanding of the genetic underpinning of migraine.
de Boer I et al.
Handbook of Clinical Neurology, 2023
The emerging role of the HTRA1 protease in brain microvascular disease.
Haffner C
Frontiers in Dementia, 2023
Rare Amyloid Precursor Protein Point Mutations Recapitulate Worldwide Migration and Admixture in Healthy Individuals: Implications for the Study of Neurodegeneration.
Abondio P et al.
International Journal of Molecular Sciences, 2022
Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy.
Shirzadi Z et al.
Annals of Neurology, 2022
Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy.
Vervuurt M et al.
Neuropathology and Applied Neurobiology, 2022
Cerebellar hemorrhages in patients with Dutch-type hereditary cerebral amyloid angiopathy.
Voigt S et al.
International Journal of Stroke : Official Journal of the International Stroke Society, 2022
Modeling neurodegenerative disorders in zebrafish.
Bashirzade AA et al.
Neuroscience and Biobehavioral Reviews, 2022