Varaico: Literature-Extracted Genetic Variants

Gene:APP
Variant:p.E674K
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APP

NM_000484.4:p.E674K

Associated Papers

Insertion of the Icelandic Mutation (A673T) by Prime Editing: A Potential Preventive Treatment for Familial and Sporadic Alzheimer's Disease.

Tremblay G et al.

The Crispr Journal, 2022

Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro.

Guyon A et al.

Molecular Therapy. Nucleic Acids, 2021

Genetic architecture of common non-Alzheimer's disease dementias.

Guerreiro R et al.

Neurobiology of Disease, 2020

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies.

Orme T et al.

Acta Neuropathologica Communications, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."