Varaico: Literature-Extracted Genetic Variants

Gene:APP
Variant:p.N660Y
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APP

NM_000484.4:p.N660Y

Associated Papers

The landscape of autosomal-dominant Alzheimer's disease: global distribution and age of onset.

Liu H et al.

Brain : a Journal of Neurology, 2025

39903689 (PubMed )
Supplement: awaf038_supplementary_data.zip › 2-Supplemental_Table1_AR_20250121_JLliF.pdf

Genomics and Functional Genomics of Alzheimer's Disease.

Kamboh MI

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics, 2022

Processing of Mutant β-Amyloid Precursor Protein and the Clinicopathological Features of Familial Alzheimer's Disease.

Bi C et al.

Aging and Disease, 2019

Monoaminergic neuropathology in Alzheimer's disease.

Šimić G et al.

Progress in Neurobiology, 2017

Alzheimer's disease risk genes and mechanisms of disease pathogenesis.

Karch CM et al.

Biological Psychiatry, 2015

Rare Variants and Transcriptomics in Alzheimer disease.

Humphries C et al.

Current Genetic Medicine Reports, 2014

Absence of A673T amyloid-β precursor protein variant in Alzheimer's disease and other neurological diseases.

Ting SK et al.

Neurobiology of Aging, 2013

A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.

Jonsson T et al.

Nature, 2012

Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families.

Cruchaga C et al.

Plos One, 2012

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