Associated Papers
Upregulation of MAM by C99 disrupts ACSL4 activity and phospholipid homeostasis in Alzheimer's disease models.
Montesinos J et al.
Biorxiv : the Preprint Server for Biology, 2025
Reciprocal modulation between amyloid precursor protein and synaptic membrane cholesterol revealed by live cell imaging.
DelBove CE et al.
Neurobiology of Disease, 2019
Specific Binding of Cholesterol to the Amyloid Precursor Protein: Structure of the Complex and Driving Forces Characterized in Molecular Detail.
Nierzwicki Ł et al.
The Journal of Physical Chemistry Letters, 2015
Perturbations of the straight transmembrane α-helical structure of the amyloid precursor protein affect its processing by γ-secretase.
Lemmin T et al.
The Journal of Biological Chemistry, 2014
The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol.
Barrett PJ et al.
Science (new York, N.y.), 2012
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