Varaico: Literature-Extracted Genetic Variants

Gene:AR
Variant:p.P12A
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AR

NM_000044.6:p.P12A

Associated Papers

Androgen Insensitivity Syndrome: Clinical Phenotype and Molecular Analysis in a Single Tertiary Center Cohort

Touzon MS et al.

Journal of Clinical Research in Pediatric Endocrinology, 2019

Quantitative evaluation of PPAR-γ2 Pro12Ala polymorphism with hypertension.

Yang W et al.

Herz, 2018

Association of PPAR-γ2 and β3-AR Polymorphisms With Postmenopausal Hypertension.

Grygiel-Górniak B et al.

Journal of Clinical Hypertension (greenwich, Conn.), 2015

The role of epistasis in the etiology of Polycystic Ovary Syndrome among Indian women: SNP-SNP and SNP-environment interactions.

Dasgupta S et al.

Annals of Human Genetics, 2013

Correlation of peroxisome proliferator-activated receptor (PPAR-γ) mRNA expression with Pro12Ala polymorphism in obesity.

Berhouma R et al.

Biochemical Genetics, 2013

The association between the Pro12Ala variant in the PPARγ2 gene and type 2 diabetes mellitus and obesity in a Chinese population.

Wang X et al.

Plos One, 2013

Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS).

Jones MR et al.

Steroids, 2012

[Meta-analysis of the association of Pro12Ala polymorphism of peroxisome proliferator activated receptor gamma gene with type 2 diabetes in Chinese Han population].

Guo WL et al.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae, 2011

Peroxisome proliferators-activated receptor γ2 Pro12Ala variant is associated with body mass index in non-alcoholic fatty liver disease patients.

Gupta AC et al.

Hepatology International, 2010

PPARG: Gene Expression Regulation and Next-Generation Sequencing for Unsolved Issues.

Costa V et al.

Ppar Research, 2010

Association of the Pro12Ala polymorphism in peroxisome proliferator-activated receptor gamma2 with decreased basic metabolic rate in women with polycystic ovary syndrome.

Koika V et al.

European Journal of Endocrinology, 2009

Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population.

Wang C et al.

Diabetes, 2009

Association of the peroxisome proliferator-activated receptor-gamma2 Pro12Ala but not the C1431T gene variants with lower body mass index in Type 2 diabetes.

Mohamed MB et al.

Journal of Endocrinological Investigation, 2007

Genetic determinants of HDL: monogenic disorders and contributions to variation.

Klos KL et al.

Current Opinion in Cardiology, 2007

Association of pro12Ala polymorphism in the peroxisome proliferative-activated receptor gamma2 gene with obesity and hypertension in Korean women.

Kim K et al.

Journal of Nutritional Science and Vitaminology, 2007

APOC3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome.

Miller M et al.

Archives of Medical Research, 2007

Heterogeneous effect of peroxisome proliferator-activated receptor gamma2 Ala12 variant on type 2 diabetes risk.

Ludovico O et al.

Obesity (silver Spring, Md.), 2007

Overcoming the winner's curse: estimating penetrance parameters from case-control data.

Zollner S et al.

American Journal of Human Genetics, 2007

Association of a common haplotype of hepatocyte nuclear factor 1alpha with type 2 diabetes in Chinese population.

Wang CR et al.

Biomedical and Environmental Sciences : Bes, 2007

The PPARgamma Pro12Ala polymorphism is not associated with body mass index or waist circumference among Hispanics from Colorado.

Nelson TL et al.

Annals of Nutrition & Metabolism, 2007

Association between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma 2 and myocardial infarction in the Chinese Han population.

Li L et al.

Clinical Cardiology, 2006

[A study on the association between polymorphism of the interleukin-4 receptor alpha gene and bronchial asthma in a population of Han nationality].

Tang Y et al.

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, 2006

The difference of mutation in the peroxisome proliferator activated receptor gamma2 gene among people at high altitudes and low altitudes in Bolivia.

Karasaki Y et al.

Journal of Uoeh, 2005

Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma2 gene on rosiglitazone response in type 2 diabetes.

Kang ES et al.

Clinical Pharmacology and Therapeutics, 2005

The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study.

Vänttinen M et al.

The Journal of Clinical Endocrinology and Metabolism, 2005

Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population.

Ghoussaini M et al.

Bmc Medical Genetics, 2005

Androgen receptor mutations in high-grade prostate cancer before hormonal therapy.

Thompson J et al.

Laboratory Investigation; a Journal of Technical Methods and Pathology, 2003

Common gene polymorphisms and nutrition: emerging links with pathogenesis of multifactorial chronic diseases (review).

Loktionov A

The Journal of Nutritional Biochemistry, 2003

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians.

Muller YL et al.

Diabetes, 2003

Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study.

Kao WH et al.

Diabetes, 2003

Effect of the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor (PPAR) gamma2 gene on the expression of PPARgamma target genes in adipose tissue of massively obese subjects.

Kolehmainen M et al.

The Journal of Clinical Endocrinology and Metabolism, 2003

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study.

Lindi VI et al.

Diabetes, 2002

Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.

Stefan N et al.

Diabetes, 2001

Evidence for gene-nutrient interaction at the PPARgamma locus.

Luan J et al.

Diabetes, 2001

Pro12Ala mutation in the peroxisome proliferator-activated receptor gamma2 (PPARgamma2) and severe obesity: a case-control study.

Vaccaro O et al.

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 2000

The peroxisome proliferator-activated receptor gamma 2 Pro12Ala mutation is associated with early onset extreme obesity and reduced fasting glucose.

Li WD et al.

Molecular Genetics and Metabolism, 2000

The Pro12Ala variant of peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) is associated with measures of obesity in Mexican Americans.

Cole SA et al.

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 2000

The Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes.

Clement K et al.

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 2000

Impact of the Peroxisome Proliferator Activated Receptor gamma2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus.

Meirhaeghe A et al.

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity, 2000

The Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma2 gene is not associated with postprandial responses to glucose or fat tolerance tests in young healthy subjects: the European Atherosclerosis Research Study II.

Poirier O et al.

Journal of Molecular Medicine (berlin, Germany), 2000

Pro12Ala substitution in the peroxisome proliferator-activated receptor-gamma2 is not associated with type 2 diabetes.

Mancini FP et al.

Diabetes, 1999

Missense variants in the human peroxisome proliferator-activated receptor-gamma2 gene in lean and obese subjects.

Hamann A et al.

European Journal of Endocrinology, 1999

Endocrinological and genetic studies in patients with Polycystic Ovary Syndrome (PCOS).

Ghanaati Z et al.

Neuro Endocrinology Letters, 1999

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