Varaico: Literature-Extracted Genetic Variants

Gene:ARAF
Variant:p.Y301D
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ARAF

NM_001654.5:p.Y301D

Associated Papers

The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.

Ryan MB et al.

Cancer Discovery, 2024

38588399 (PubMed )
Supplement: cd-24-0139_supplementary_methods_suppstm.docx

RAF kinases are stabilized and required for dendritic cell differentiation and function.

Riegel K et al.

Cell Death and Differentiation, 2020

Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription.

Rauch J et al.

Cancer Research, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."