Associated Papers
Unraveling the enigma of mental disorders: a genetics-first approach and the role of mouse models based on rare disease-susceptible genome variants.
Kondo R et al.
Nagoya Journal of Medical Science, 2025
Gnao1 is a molecular switch that regulates the Rho signaling pathway in differentiating neurons.
Taira R et al.
Scientific Reports, 2024
Genomic and Reverse Translational Analysis Discloses a Role for Small GTPase RhoA Signaling in the Pathogenesis of Schizophrenia: Rho-Kinase as a Novel Drug Target.
Tanaka R et al.
International Journal of Molecular Sciences, 2023
Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK.
Nussinov R et al.
Biophysical Reviews, 2023
The genetic architecture of schizophrenia: review of large-scale genetic studies.
Kato H et al.
Journal of Human Genetics, 2023
Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons.
Hada K et al.
Molecular Brain, 2021
ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk.
Sekiguchi M et al.
Translational Psychiatry, 2020
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