Varaico: Literature-Extracted Genetic Variants

Gene:ARHGEF1
Variant:p.E27K
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ARHGEF1

NM_004706.4:p.E27K

Associated Papers

A conserved hydrophobic surface of the LARG pleckstrin homology domain is critical for RhoA activation in cells.

Aittaleb M et al.

Cellular Signalling, 2009

Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.

Chen Z et al.

Nature Structural & Molecular Biology, 2005

Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF.

Chen Z et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."