Varaico: Literature-Extracted Genetic Variants

Gene:ARIH1
Variant:p.E431A
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ARIH1

NM_005744.5:p.E431A

Associated Papers

E2 variants for probing E3 ubiquitin ligase activities.

Du J et al.

Proceedings of the National Academy of Sciences of the United States of America, 2026

Cullin-independent recognition of HHARI substrates by a dynamic RBR catalytic domain.

Reiter KH et al.

Structure (london, England : 1993), 2022

Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.

Horn-Ghetko D et al.

Nature, 2021

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

Kelsall IR et al.

The Journal of Biological Chemistry, 2019

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes.

Kelsall IR et al.

The Embo Journal, 2013

Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism.

Duda DM et al.

Structure (london, England : 1993), 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."