Varaico: Literature-Extracted Genetic Variants

Gene:ARIH2
Variant:p.E455A
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ARIH2

NM_006321.4:p.E455A

Associated Papers

E2 variants for probing E3 ubiquitin ligase activities.

Du J et al.

Proceedings of the National Academy of Sciences of the United States of America, 2026

Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.

Horn-Ghetko D et al.

Nature Structural & Molecular Biology, 2024

CUL5-ARIH2 E3-E3 ubiquitin ligase structure reveals cullin-specific NEDD8 activation.

Kostrhon S et al.

Nature Chemical Biology, 2021

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.

Kelsall IR et al.

The Journal of Biological Chemistry, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."