Varaico: Literature-Extracted Genetic Variants

Gene:ARL11
Variant:p.C148R
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ARL11

NM_138450.6:p.C148R

Associated Papers

Multifaceted role of primary cilia and ciliary proteins: A potential nexus for hedgehog signaling and prostate cancer.

Kaushal JB et al.

Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2026

Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Montazeri Z et al.

Gut, 2020

31818908 (PubMed )
Supplement: gutjnl-2019-319313supp003.pdf

The Role of ARF Family Proteins and Their Regulators and Effectors in Cancer Progression: A Therapeutic Perspective.

Casalou C et al.

Frontiers in Cell and Developmental Biology, 2020

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM11_ESM.xlsx › SD7_-_Drug_Targets

ARL11 regulates lipopolysaccharide-stimulated macrophage activation by promoting mitogen-activated protein kinase (MAPK) signaling.

Arya SB et al.

The Journal of Biological Chemistry, 2018

ARLTS1, potential candidate gene in familial aggregation of hematological malignancies.

Hamadou WS et al.

Bulletin Du Cancer, 2017

ARLTS1 polymorphism is associated with an increased risk of familial cancer: evidence from a meta-analysis.

Jiang Y et al.

Hereditary Cancer in Clinical Practice, 2017

The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas.

Lim CH et al.

Oncotarget, 2016

27175599 (PubMed )
Supplement: oncotarget-07-39758-s006.xlsx › TableS5

A common founding clone with TP53 and PTEN mutations gives rise to a concurrent germ cell tumor and acute megakaryoblastic leukemia.

Lu C et al.

Cold Spring Harbor Molecular Case Studies, 2016

27148581 (PubMed )
Supplement: supp_2.1.a000687_Supp_Table_2.xlsx › germline.missense

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA

The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.

Tang X et al.

Nucleic Acids Research, 2014

25352556 (PubMed )
Supplement: supp_gku1005_nar-01266-met-n-2014-File012.xlsx › TCGA-A2-A04Y-01A.domain

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

ARLTS1 and prostate cancer risk--analysis of expression and regulation.

Siltanen S et al.

Plos One, 2013

Seeking genetic susceptibility variants for colorectal cancer: the EPICOLON consortium experience.

Castellví-Bel S et al.

Mutagenesis, 2012

A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.

Abulí A et al.

British Journal of Cancer, 2011

ARLTS1, MDM2 and RAD51 gene variations are associated with familial breast cancer.

Akisik E et al.

Molecular Biology Reports, 2011

Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.

Siltanen S et al.

Plos One, 2011

Clinical and genetic analysis of 18 pancreatic carcinoma/melanoma-prone families.

Bartsch DK et al.

Clinical Genetics, 2010

[Polymorphism of ARLTS1 gene in early-onset ovarian cancer].

Yang XY et al.

Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition, 2009

Association of the ARLTS1 variants with familial ovarian cancer risk in China.

Yang XY et al.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, 2009

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.

Ley TJ et al.

Nature, 2008

18987736 (PubMed )
Supplement: NIHMS71093-supplement-1.pdf

ARLTS1 germline variants and the risk for breast, prostate, and colorectal cancer.

Siltanen S et al.

European Journal of Human Genetics : Ejhg, 2008

ARLTS1 - a novel tumor suppressor gene.

Yendamuri S et al.

Cancer Letters, 2008

Tumor suppressor functions of ARLTS1 in lung cancers.

Yendamuri S et al.

Cancer Research, 2007

Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer.

Castellví-Bel S et al.

Carcinogenesis, 2007

No association of ARLTS1 polymorphisms and risk for familial chronic lymphocytic leukaemia.

Ng D et al.

British Journal of Haematology, 2007

ARLTS1 polymorphisms and basal cell carcinoma of the skin.

Li X et al.

Hereditary Cancer in Clinical Practice, 2007

ARLTS1 variants and risk of colorectal cancer.

Frank B et al.

Cancer Letters, 2006

Relationship between ARLTS1 polymorphisms and risk of chronic lymphocytic leukemia.

Sellick GS et al.

Leukemia Research, 2006

Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.

Petrocca F et al.

Cancer Research, 2006

ARLTS1 variants and melanoma risk.

Frank B et al.

International Journal of Cancer, 2006

Association of the ARLTS1 Cys148Arg variant with familial breast cancer risk.

Frank B et al.

International Journal of Cancer, 2006

Familial cancer associated with a polymorphism in ARLTS1.

Sellick GS et al.

The New England Journal of Medicine, 2006

Familial cancer associated with a polymorphism in ARLTS1.

Calin GA et al.

The New England Journal of Medicine, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."