Associated Papers
Knocking out ARL13B completely abolishes primary ciliogenesis in cell lines.
Mahajan D et al.
Scientific Reports, 2025
Smoothened and ARL13B are critical in mouse for superior cerebellar peduncle targeting.
Suciu SK et al.
Genetics, 2021
Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models.
Guo J et al.
Developmental Cell, 2019
The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance.
Ferent J et al.
Cell Reports, 2019
The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment.
Hanke-Gogokhia C et al.
The Journal of Biological Chemistry, 2017
A novel homozygous ARL13B variant in patients with Joubert syndrome impairs its guanine nucleotide-exchange factor activity.
Rafiullah R et al.
European Journal of Human Genetics : Ejhg, 2017
Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity.
Guo J et al.
Developmental Cell, 2017
Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).
Ivanova AA et al.
The Journal of Biological Chemistry, 2017
Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E.
Nozaki S et al.
Journal of Cell Science, 2017
Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts.
Li Y et al.
Journal of the American Society of Nephrology : Jasn, 2016
Arl13b regulates Shh signaling from both inside and outside the cilium.
Mariani LE et al.
Molecular Biology of the Cell, 2016
MKS1 regulates ciliary INPP5E levels in Joubert syndrome.
Slaats GG et al.
Journal of Medical Genetics, 2016
Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity.
Thomas S et al.
European Journal of Human Genetics : Ejhg, 2015
Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain.
Cevik S et al.
Plos Genetics, 2013
ARL13B, PDE6D, and CEP164 form a functional network for INPP5E ciliary targeting.
Humbert MC et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012
Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex.
Higginbotham H et al.
Developmental Cell, 2012