Varaico: Literature-Extracted Genetic Variants

Gene:ARRB1
Variant:p.V53D
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ARRB1

NM_004041.5:p.V53D

Associated Papers

Agonist-induced up-regulation of human somatostatin receptor type 1 is regulated by beta-arrestin-1 and requires an essential serine residue in the receptor C-tail.

Ramírez JL et al.

Biochimica Et Biophysica Acta, 2005

Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor.

Madziva MT et al.

British Journal of Pharmacology, 2005

Serine residues 338 and 339 in the carboxyl-terminal tail of the type II gonadotropin-releasing hormone receptor are critical for beta-arrestin-independent internalization.

Ronacher K et al.

Endocrinology, 2004

Properties of rat melanin-concentrating hormone receptor 1 internalization.

Saito Y et al.

Peptides, 2004

Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus and the (D/N)PXXY motif.

Chen Z et al.

The Journal of Biological Chemistry, 2002

Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced cooh terminus in agonist-promoted receptor internalization.

Parent JL et al.

The Journal of Biological Chemistry, 1999

Constitutively active alpha-1b adrenergic receptor mutants display different phosphorylation and internalization features.

Mhaouty-Kodja S et al.

Molecular Pharmacology, 1999

Characterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanisms.

Orsini MJ et al.

The Journal of Biological Chemistry, 1998

Dynamin and beta-arrestin reveal distinct mechanisms for G protein-coupled receptor internalization.

Zhang J et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."