Varaico: Literature-Extracted Genetic Variants

Gene:AS3MT
Variant:p.M287T
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AS3MT

NM_020682.4:p.M287T

Associated Papers

AS3MT Gene Variant Shows Association with Skin Lesions in an Arsenic Exposed Population of India.

Ghosh S et al.

Biological Trace Element Research, 2025

The Impact of Genetic Polymorphisms for Detecting Genotoxicity in Workers Occupationally Exposed to Metals: A Systematic Review.

Pinto TG et al.

Journal of Applied Toxicology : Jat, 2025

Effects of methylation of arginine residue 83 on the enzymatic activity of human arsenic (+3 oxidation state) methyltransferase.

Sumi D et al.

Toxicology in Vitro : an International Journal Published in Association With Bibra, 2023

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM10_ESM.xlsx › Supplementary_Data_7

Environmental exposures and breast cancer risk in the context of underlying susceptibility: A systematic review of the epidemiological literature.

Zeinomar N et al.

Environmental Research, 2020

Association of intronic polymorphisms (rs1549339, rs13402242) and mRNA expression variations in PSMD1 gene in arsenic-exposed workers.

Ahmad S et al.

Environmental Science and Pollution Research International, 2020

Recent population genomic insights into the genetic basis of arsenic tolerance in humans: the difficulties of identifying positively selected loci in strongly bottlenecked populations.

Apata M et al.

Heredity, 2020

Genetic susceptibility to breast cancer risk associated with inorganic arsenic exposure.

Gamboa-Loira B et al.

Environmental Toxicology and Pharmacology, 2017

Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity.

Li J et al.

Chemical Research in Toxicology, 2017

Associations between arsenic (+3 oxidation state) methyltransferase (AS3MT) and N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) polymorphisms, arsenic metabolism, and cancer risk in a chilean population.

de la Rosa R et al.

Environmental and Molecular Mutagenesis, 2017

Human adaptation to arsenic in Andean populations of the Atacama Desert.

Apata M et al.

American Journal of Physical Anthropology, 2017

Relation of polymorphism of arsenic metabolism genes to arsenic methylation capacity and developmental delay in preschool children in Taiwan.

Hsieh RL et al.

Toxicology and Applied Pharmacology, 2017

Frequency of M287T/AS3MT Single Nucleotide Polymorphism in an Iranian Population.

Farhid F et al.

International Journal of Hematology-oncology and Stem Cell Research, 2017

Interactive Influence of N6AMT1 and As3MT Genetic Variations on Arsenic Metabolism in the Population of Inner Mongolia, China.

Chen X et al.

Toxicological Sciences : an Official Journal of the Society of Toxicology, 2017

Arsenic and subclinical vascular damage in a sample of Italian young adults: a cross-sectional analysis.

Stea F et al.

Environmental Science and Pollution Research International, 2016

Association of single nucleotide polymorphism with arsenic-induced skin lesions and genetic damage in exposed population of West Bengal, India.

Das N et al.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2016

Association Between Variants in Arsenic (+3 Oxidation State) Methyltranserase (AS3MT) and Urinary Metabolites of Inorganic Arsenic: Role of Exposure Level.

Xu X et al.

Toxicological Sciences : an Official Journal of the Society of Toxicology, 2016

Association between polymorphisms in arsenic metabolism genes and urinary arsenic methylation profiles in girls and boys chronically exposed to arsenic.

Recio-Vega R et al.

Environmental and Molecular Mutagenesis, 2016

Analysis of maternal polymorphisms in arsenic (+3 oxidation state)-methyltransferase AS3MT and fetal sex in relation to arsenic metabolism and infant birth outcomes: Implications for risk analysis.

Drobná Z et al.

Reproductive Toxicology (elmsford, N.y.), 2016

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus.

Li M et al.

Nature Medicine, 2016

Influence of the level of arsenic (As) exposure and the presence of T860C polymorphism in human As urinary metabolic profile.

Olmos V et al.

Human & Experimental Toxicology, 2015

[Relationship between Arsenic (+3 Oxidation State) Methyltransferase Genetic Polymorphisms and Methylation Capacity of Inorganic Arsenic].

Agusa T et al.

Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene, 2015

Genetic susceptibility to arsenic-induced skin lesions and health effects: a review.

Paul S et al.

Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society, 2015

GSTO and AS3MT genetic polymorphisms and differences in urinary arsenic concentrations among residents in Bangladesh.

Rodrigues EG et al.

Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals, 2012

A case-control study of polymorphisms in xenobiotic and arsenic metabolism genes and arsenic-related bladder cancer in New Hampshire.

Lesseur C et al.

Toxicology Letters, 2012

Genome-wide association study identifies chromosome 10q24.32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh.

Pierce BL et al.

Plos Genetics, 2012

Alternative splicing variants of human arsenic (+3 oxidation state) methyltransferase.

Sumi D et al.

Biochemical and Biophysical Research Communications, 2011

Genetic variants associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase show wide variation across multiple populations.

Fujihara J et al.

Archives of Toxicology, 2011

Polymorphisms in arsenic(+III oxidation state) methyltransferase (AS3MT) predict gene expression of AS3MT as well as arsenic metabolism.

Engström K et al.

Environmental Health Perspectives, 2011

Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms.

Agusa T et al.

International Journal of Molecular Sciences, 2011

Global analysis of genetic variation in human arsenic (+3 oxidation state) methyltransferase (AS3MT).

Fujihara J et al.

Toxicology and Applied Pharmacology, 2010

Synergistic effect of polymorphisms of paraoxonase gene cluster and arsenic exposure on electrocardiogram abnormality.

Liao YT et al.

Toxicology and Applied Pharmacology, 2009

Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions.

Valenzuela OL et al.

Toxicology and Applied Pharmacology, 2009

Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions.

Schläwicke Engström K et al.

Mutation Research, 2009

Ethnic differences in five intronic polymorphisms associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene.

Fujihara J et al.

Toxicology and Applied Pharmacology, 2009

Asian specific low mutation frequencies of the M287T polymorphism in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene.

Fujihara J et al.

Mutation Research, 2008

High arsenic metabolic efficiency in AS3MT287Thr allele carriers.

Hernández A et al.

Pharmacogenetics and Genomics, 2008

Role of the Met(287)Thr polymorphism in the AS3MT gene on the metabolic arsenic profile.

Hernández A et al.

Mutation Research, 2008

Polymorphism of glutathione transferase Omega 1 in a population exposed to a high environmental arsenic burden.

Paiva L et al.

Pharmacogenetics and Genomics, 2008

Population differences in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene polymorphism detected by using genotyping method.

Fujihara J et al.

Toxicology and Applied Pharmacology, 2007

Developmental and genetic modulation of arsenic biotransformation: a gene by environment interaction?

Meza M et al.

Toxicology and Applied Pharmacology, 2007

Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina.

Schläwicke Engström K et al.

Environmental Health Perspectives, 2007

Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies.

Wood TC et al.

The Journal of Biological Chemistry, 2006

Insights into S-adenosyl-l-methionine (SAM)-dependent methyltransferase related diseases and genetic polymorphisms.

Li J et al.

Mutation Research. Reviews in Mutation Research, 0

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