Associated Papers
CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice.
Geng J et al.
Science Translational Medicine, 2025
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Narita M et al.
Nature Communications, 2022
The ASC-1 Complex Disassembles Collided Ribosomes.
Juszkiewicz S et al.
Molecular Cell, 2020
Identification of a novel trigger complex that facilitates ribosome-associated quality control in mammalian cells.
Hashimoto S et al.
Scientific Reports, 2020
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