Varaico: Literature-Extracted Genetic Variants

Gene:ATG16L1
Variant:p.D299E
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ATG16L1

NM_030803.7:p.D299E

Associated Papers

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.

Lassen KG et al.

Proceedings of the National Academy of Sciences of the United States of America, 2014

A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

Murthy A et al.

Nature, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."