Associated Papers
Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers.
Miao Y et al.
The Journal of Clinical Investigation, 2024
Loss of ATG4B and ATG4A results in two-stage cell cycle defects in pancreatic ductal adenocarcinoma cells.
Sathiyaseelan P et al.
Journal of Cell Science, 2023
Autophagy Blockage Reduces the Incidence of Pancreatic Ductal Adenocarcinoma in the Context of Mutant Trp53.
Mainz L et al.
Frontiers in Cell and Developmental Biology, 2022
Novel blood test for early biomarkers of preeclampsia and Alzheimer's disease.
Cheng S et al.
Scientific Reports, 2021
Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia.
Nakashima A et al.
Autophagy, 2020
LC3-Associated Endocytosis Facilitates β-Amyloid Clearance and Mitigates Neurodegeneration in Murine Alzheimer's Disease.
Heckmann BL et al.
Cell, 2019
Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers.
Kinsey CG et al.
Nature Medicine, 2019
TRAPPC13 modulates autophagy and the response to Golgi stress.
Ramírez-Peinado S et al.
Journal of Cell Science, 2017
Autophagy facilitates organelle clearance during differentiation of human erythroblasts: evidence for a role for ATG4 paralogs during autophagosome maturation.
Betin VM et al.
Autophagy, 2013
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