Associated Papers
Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.
Kuras M et al.
Cancers, 2025
The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.
Wang LY et al.
Innovation (cambridge (mass.)), 2025
Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review.
Hamdani S et al.
Frontiers in Genetics, 2025
Pharmacogenomics and genetic ancestry in Colombia: a study on all variant drug annotations of PharmGKB.
Acosta-Monterrosa AA et al.
Frontiers in Pharmacology, 2025
Pharmacogenetics of therapies in rheumatoid arthritis: An update.
Babiker-Mohamed MH et al.
Best Practice & Research. Clinical Rheumatology, 2024
Genetic biomarkers of methotrexate response and safety in Crohn's disease: Data from the Spanish ENEIDA registry.
Salazar J et al.
British Journal of Clinical Pharmacology, 2024
The impact of folate pathway variants on the outcome of methotrexate therapy in rheumatoid arthritis patients.
Nomair AM et al.
Clinical Rheumatology, 2024
Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.
Yang N et al.
Bmc Pediatrics, 2024
A meta-analysis of the association between the ATIC 347 C/G polymorphism and methotrexate responsiveness and toxicity in rheumatoid arthritis.
Lee YH et al.
Seminars in Arthritis and Rheumatism, 2024
Bayesian polygenic risk estimation approach to nuclear families with discordant sib-pairs for myelomeningocele.
Aguayo-Gómez A et al.
Plos One, 2024
Sensitization of Patient-Derived Colorectal Cancer Organoids to Photon and Proton Radiation by Targeting DNA Damage Response Mechanisms.
Pape K et al.
Cancers, 2022
5-Amino-4-Imidazolecarboxamide Ribonucleotide Transformylase/IMP Cyclohydrolase Polymorphisms Affect the Susceptibility to Multiple Myeloma.
Wang Y et al.
Laboratory Medicine, 2022
Genetic variations in methotrexate metabolic pathway genes influence methotrexate responses in rheumatoid arthritis patients in Malaysia.
Sha HX et al.
Scientific Reports, 2022
Impact of Variants in the ATIC and ARID5B Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia.
Cereja Pantoja KBC et al.
Genes, 2022
Is Pharmacogenetic Panel Testing Applicable to Low-Dose Methotrexate in Rheumatoid Arthritis? - A Case Report.
Jeiziner C et al.
Pharmacogenomics and Personalized Medicine, 2022
Association between high-dose methotrexate-induced toxicity and polymorphisms within methotrexate pathway genes in acute lymphoblastic leukemia.
Xu M et al.
Frontiers in Pharmacology, 2022
Association of MTHFR and ABCB1 polymorphisms with MTX-induced mucositis in Chinese paediatric patients with acute lymphoblastic leukaemia, lymphoma or osteosarcoma-A retrospective cohort study.
Gong Y et al.
Journal of Clinical Pharmacy and Therapeutics, 2021
Comprehensive Genomic and Transcriptomic Analysis of Three Synchronous Primary Tumours and a Recurrence from a Head and Neck Cancer Patient.
Bresadola L et al.
International Journal of Molecular Sciences, 2021
Systematic Review of Pharmacogenetic Factors That Influence High-Dose Methotrexate Pharmacokinetics in Pediatric Malignancies.
Taylor ZL et al.
Cancers, 2021
Polymorphism of genes involved in methotrexate pathway: Predictors of response to methotrexate therapy in Indian rheumatoid arthritis patients.
Singh A et al.
International Journal of Rheumatic Diseases, 2021
Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing.
Aboul-Soud MAM et al.
Saudi Journal of Biological Sciences, 2021
The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis.
Song Z et al.
Frontiers in Pharmacology, 2021
AICA-ribosiduria due to ATIC deficiency: Delineation of the phenotype with three novel cases, and long-term update on the first case.
Ramond F et al.
Journal of Inherited Metabolic Disease, 2020
The impact of single nucleotide polymorphisms in ADORA2A and ADORA3 genes on the early response to methotrexate and presence of therapy side effects in children with juvenile idiopathic arthritis: Results of a preliminary study.
Roszkiewicz J et al.
International Journal of Rheumatic Diseases, 2020
Pharmacogenetic aspects of methotrexate in a cohort of Colombian patients with rheumatoid arthritis.
Londono J et al.
Biomedical Reports, 2020
Association between the TPMT*3C (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon Region.
Cardoso de Carvalho D et al.
Genes, 2020
Using pharmacogenetics to predict methotrexate response in rheumatoid arthritis patients.
Szostak B et al.
Expert Opinion on Drug Metabolism & Toxicology, 2020
From astrocytoma to glioblastoma: a clonal evolution study.
Yang F et al.
Febs Open Bio, 2020
Association of genes ARID5B, CEBPE and folate pathway with acute lymphoblastic leukemia in a population from the Brazilian Amazon region.
Carvalho DC et al.
Leukemia Research Reports, 2020
Are gene polymorphisms related to adverse events of methotrexate in patients with rheumatoid arthritis? A retrospective cohort study based on an updated meta-analysis.
Huang J et al.
Therapeutic Advances in Chronic Disease, 2020
Mutant Proteomics of Lung Adenocarcinomas Harboring Different EGFR Mutations.
Nishimura T et al.
Frontiers in Oncology, 2020
Accumulation of rare coding variants in genes implicated in risk of human cleft lip with or without cleft palate.
Marini NJ et al.
American Journal of Medical Genetics. Part A, 2019
Targeted next generation sequencing as a tool for precision medicine.
Gulilat M et al.
Bmc Medical Genomics, 2019
Genetic markers in methotrexate treatments.
Giletti A et al.
The Pharmacogenomics Journal, 2018
Risk factors for abnormal hepatic enzyme elevation by methotrexate treatment in patients with rheumatoid arthritis: A hospital based-cohort study.
Hakamata J et al.
Modern Rheumatology, 2018
Identification of ATIC as a Novel Target for Chemoradiosensitization.
Liu X et al.
International Journal of Radiation Oncology, Biology, Physics, 2018
Clinical Pharmacogenetic Models of Treatment Response to Methotrexate Monotherapy in Slovenian and Serbian Rheumatoid Arthritis Patients: Differences in Patient's Management May Preclude Generalization of the Models.
Jenko B et al.
Frontiers in Pharmacology, 2018
Factors Predicting the Therapeutic Response to Methotrexate in Japanese Patients with Rheumatoid Arthritis: A Hospital-Based Cohort Study.
Hakamata J et al.
Biological & Pharmaceutical Bulletin, 2018
Genetic Polymorphisms of TYMS, MTHFR, ATIC, MTR, and MTRR Are Related to the Outcome of Methotrexate Therapy for Rheumatoid Arthritis in a Chinese Population.
Lv S et al.
Frontiers in Pharmacology, 2018
ATIC Gene Polymorphism and Histologic Response to Chemotherapy in Pediatric Osteosarcoma.
Park JA et al.
Journal of Pediatric Hematology/oncology, 2017
Association Between MTHFR C677T Polymorphism and Methotrexate Treatment Outcome in Rheumatoid Arthritis Patients: A Systematic Review and Meta-Analysis.
Shao W et al.
Genetic Testing and Molecular Biomarkers, 2017
Lack of association between MTHFR A1298C polymorphism and outcome of methotrexate treatment in rheumatoid arthritis patients: evidence from a systematic review and meta-analysis.
Fan H et al.
International Journal of Rheumatic Diseases, 2017