Associated Papers
Exploring CSF microRNA signatures as diagnostic biomarkers in adult-type diffuse gliomas.
Pirhoushiaran M et al.
Non-coding Rna Research, 2026
Microhomology-mediated end joining acts directly on replication forks to repair single-ended double strand breaks.
Li S et al.
Biorxiv : the Preprint Server for Biology, 2026
Progress of ATM inhibitors: Opportunities and challenges.
Du S et al.
European Journal of Medicinal Chemistry, 2024
ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma.
Laverty DJ et al.
Nature Communications, 2024
Multiplex single-cell chemical genomics reveals the kinase dependence of the response to targeted therapy.
McFaline-Figueroa JL et al.
Cell Genomics, 2024
KPT330 promotes the sensitivity of glioblastoma to olaparib by retaining SQSTM1 in the nucleus and disrupting lysosomal function.
Wang LH et al.
Autophagy, 2024
Nuclear transport surveillance of p53 by nuclear pores in glioblastoma.
Ikliptikawati DK et al.
Cell Reports, 2023
ATM-SPARK: A GFP phase separation-based activity reporter of ATM.
Li X et al.
Science Advances, 2023
AMPK increases expression of ATM through transcriptional factor Sp1 and induces radioresistance under severe hypoxia in glioblastoma cell lines.
Hashimoto T et al.
Biochemical and Biophysical Research Communications, 2022
A Tale of Two Checkpoints: ATR Inhibition and PD-(L)1 Blockade.
Ngoi NYL et al.
Annual Review of Medicine, 2022
Cancer cell stemness, responses to experimental genotoxic treatments, cytomegalovirus protein expression and DNA replication stress in pediatric medulloblastomas.
Bartek J et al.
Cell Cycle (georgetown, Tex.), 2020
Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.
Karlin J et al.
Molecular Cancer Therapeutics, 2018
ATM in breast and brain tumors: a comprehensive review.
Estiar MA et al.
Cancer Biology & Medicine, 2018
The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.
Durant ST et al.
Science Advances, 2018
An association between low-dose hyper-radiosensitivity and the early G2-phase checkpoint in normal fibroblasts of cancer patients.
Słonina D et al.
Dna Repair, 2016
Linking ATM Promoter Methylation to Cell Cycle Protein Expression in Brain Tumor Patients: Cellular Molecular Triangle Correlation in ATM Territory.
Mehdipour P et al.
Molecular Neurobiology, 2015
Evaluation of novel imidazotetrazine analogues designed to overcome temozolomide resistance and glioblastoma regrowth.
Ramirez YP et al.
Molecular Cancer Therapeutics, 2015
ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents.
Agnihotri S et al.
Cancer Discovery, 2014
MiR-26a enhances the radiosensitivity of glioblastoma multiforme cells through targeting of ataxia-telangiectasia mutated.
Guo P et al.
Experimental Cell Research, 2014
ATM regulates Cdt1 stability during the unperturbed S phase to prevent re-replication.
Iwahori S et al.
Cell Cycle (georgetown, Tex.), 2014
The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses.
Mukherjee B et al.
Neoplasia (new York, N.y.), 2012
ATM protein kinase: the linchpin of cellular defenses to stress.
Bhatti S et al.
Cellular and Molecular Life Sciences : Cmls, 2011
Quantification of gammaH2AX foci in response to ionising radiation.
Mah LJ et al.
Journal of Visualized Experiments : Jove, 2010
Caffeine confers radiosensitization of PTEN-deficient malignant glioma cells by enhancing ionizing radiation-induced G1 arrest and negatively regulating Akt phosphorylation.
Sinn B et al.
Molecular Cancer Therapeutics, 2010
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies.
Veeriah S et al.
Nature Genetics, 2010
ATM acts downstream of ATR in the DNA damage response signaling of bystander cells.
Burdak-Rothkamm S et al.
Cancer Research, 2008
Transition in survival from low-dose hyper-radiosensitivity to increased radioresistance is independent of activation of ATM Ser1981 activity.
Krueger SA et al.
International Journal of Radiation Oncology, Biology, Physics, 2007
Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity.
Roy K et al.
Biochemical and Biophysical Research Communications, 2006
A role of p73 in mitotic exit.
Merlo P et al.
The Journal of Biological Chemistry, 2005
Aberrant splicing of the ATM gene associated with shortening of the intronic mononucleotide tract in human colon tumor cell lines: a novel mutation target of microsatellite instability.
Ejima Y et al.
International Journal of Cancer, 2000
Determination of the genotype of a panel of human tumor cell lines for the human homologues of yeast cell cycle checkpoint control genes: identification of cell lines carrying homoallelic missense base substitutions.
Ejima Y et al.
Somatic Cell and Molecular Genetics, 1999