Associated Papers
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
Functional assessment of all ATM SNVs using prime editing and deep learning.
Lee KS et al.
Cell, 2025
ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion.
Menolfi D et al.
Cell & Bioscience, 2020
Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance.
Di Domenico EG et al.
Biomed Research International, 2014
Protein phosphatase 1 inhibits p53 signaling by dephosphorylating and stabilizing Mdmx.
Lu Z et al.
Cellular Signalling, 2013
The ATM signaling network in development and disease.
Stracker TH et al.
Frontiers in Genetics, 2013
Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.
Yamamoto K et al.
The Journal of Cell Biology, 2012
Autophosphorylation and ATM activation: additional sites add to the complexity.
Kozlov SV et al.
The Journal of Biological Chemistry, 2011
Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.
Davis AJ et al.
Cell Cycle (georgetown, Tex.), 2010
Phosphorylation and degradation of MdmX is inhibited by Wip1 phosphatase in the DNA damage response.
Zhang X et al.
Cancer Research, 2009
Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo.
Daniel JA et al.
The Journal of Cell Biology, 2008
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.
Lavin MF
Oncogene, 2007
DNA damage-induced signalling in ataxia-telangiectasia and related syndromes.
Lavin MF et al.
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 2007
ATM activation and DNA damage response.
Lavin MF et al.
Cell Cycle (georgetown, Tex.), 2007
Involvement of novel autophosphorylation sites in ATM activation.
Kozlov SV et al.
The Embo Journal, 2006
Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest.
Capasso H et al.
Journal of Cell Science, 2002
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: the molecular choreography.
Thompson LH
Mutation Research, 0