Associated Papers
Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop.
Qi L et al.
Iscience, 2022
The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange.
Milanovic M et al.
Cancer Research, 2021
The recent advances in non-homologous end-joining through the lens of lymphocyte development.
Wang XS et al.
Dna Repair, 2020
ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion.
Menolfi D et al.
Cell & Bioscience, 2020
Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.
Zhou Y et al.
Molecular Cell, 2017
Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance.
Di Domenico EG et al.
Biomed Research International, 2014
Loss of PPP2R2A inhibits homologous recombination DNA repair and predicts tumor sensitivity to PARP inhibition.
Kalev P et al.
Cancer Research, 2012
Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.
Yamamoto K et al.
The Journal of Cell Biology, 2012
Autophosphorylation and ATM activation: additional sites add to the complexity.
Kozlov SV et al.
The Journal of Biological Chemistry, 2011
Assembly and function of DNA double-strand break repair foci in mammalian cells.
Bekker-Jensen S et al.
Dna Repair, 2010
Multiple roles of ATM in monitoring and maintaining DNA integrity.
Derheimer FA et al.
Febs Letters, 2010
Dynamics of the PI3K-like protein kinase members ATM and DNA-PKcs at DNA double strand breaks.
Davis AJ et al.
Cell Cycle (georgetown, Tex.), 2010
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites.
So S et al.
The Journal of Cell Biology, 2009
Activation of ATM depends on chromatin interactions occurring before induction of DNA damage.
Kim YC et al.
Nature Cell Biology, 2009
Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo.
Daniel JA et al.
The Journal of Cell Biology, 2008
Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer.
Lavin MF
Nature Reviews. Molecular Cell Biology, 2008
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.
Lee JH et al.
Oncogene, 2007
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.
Lavin MF
Oncogene, 2007
ATM activation and DNA damage response.
Lavin MF et al.
Cell Cycle (georgetown, Tex.), 2007
Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo.
Pellegrini M et al.
Nature, 2006