Varaico: Literature-Extracted Genetic Variants

Gene:ATM
Variant:p.V2886insFs
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ATM

NM_000051.4:p.V2886insFs

Associated Papers

Kinase-dead ATM protein is highly oncogenic and can be preferentially targeted by Topo-isomerase I inhibitors.

Yamamoto K et al.

Elife, 2016

27304073 (PubMed )
Supplement: elife-14709-supp1.xlsx › Supplementary_Information_1A

ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region.

Pan-Hammarström Q et al.

Journal of Immunology (baltimore, Md. : 1950), 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."