Varaico: Literature-Extracted Genetic Variants

Gene:AURKA
Variant:p.S361*
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AURKA

NM_198437.3:p.S361*

Associated Papers

Targeted mutation detection in breast cancer using MammaSeq™.

Smith NG et al.

Breast Cancer Research : Bcr, 2019

30736836 (PubMed )
Supplement: 13058_2019_1102_MOESM2_ESM.xlsx › Sheet1

Computational investigation of cancer-associated molecular mechanism in Aurora A (S155R) mutation.

Kumar A et al.

Cell Biochemistry and Biophysics, 2013

Aurora-A expressing tumour cells are deficient for homology-directed DNA double strand-break repair and sensitive to PARP inhibition.

Sourisseau T et al.

Embo Molecular Medicine, 2010

A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.

Bibby RA et al.

The Journal of Biological Chemistry, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."