Varaico: Literature-Extracted Genetic Variants

Gene:AURKA
Variant:p.C290S
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AURKA

NM_198437.3:p.C290S

Associated Papers

Aurora A binds to the transactivation domain of c-Myc and recognizes the phosphorylated N-terminal degron motif.

Joshi N et al.

The Biochemical Journal, 2025

Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity.

Byrne DP et al.

Science Signaling, 2020

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation.

Ruff EF et al.

Elife, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."