Varaico: Literature-Extracted Genetic Variants

Gene:AURKA
Variant:p.T288A
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AURKA

NM_198437.3:p.T288A

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5

Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors.

Damodaran AP et al.

The Journal of Biological Chemistry, 2025

Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation.

Fang Z et al.

Cell Reports, 2023

Redox priming promotes Aurora A activation during mitosis.

Lim DC et al.

Science Signaling, 2020

Insights into Aurora-A kinase activation using unnatural amino acids incorporated by chemical modification.

Rowan FC et al.

Acs Chemical Biology, 2013

p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation.

Wu CC et al.

Cell Cycle (georgetown, Tex.), 2012

Aurora-A kinase phosphorylation of Aurora-A kinase interacting protein (AIP) and stabilization of the enzyme-substrate complex.

Katayama H et al.

Journal of Cellular Biochemistry, 2007

HEF1-dependent Aurora A activation induces disassembly of the primary cilium.

Pugacheva EN et al.

Cell, 2007

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