Associated Papers
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S5
Dr. Kinase: predicting the drug-resistance hotspots of protein kinases.
Lin S et al.
Nucleic Acids Research, 2025
40308214 (PubMed )
Supplement: gkaf366_supplemental_file.zip › Supplementary_Table_S1.xlsx › Table_S1
A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant.
Barakat KH et al.
Molecular Pharmaceutics, 2013
Insights into Aurora-A kinase activation using unnatural amino acids incorporated by chemical modification.
Rowan FC et al.
Acs Chemical Biology, 2013
A cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2.
Bibby RA et al.
The Journal of Biological Chemistry, 2009
Aurora kinase inhibitors as anticancer molecules.
Katayama H et al.
Biochimica Et Biophysica Acta, 0
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