Associated Papers
Discriminating activating, deactivating and resistance variants in protein kinases.
Singh G et al.
Genome Medicine, 2025
A kinase-independent function for AURORA-A in replisome assembly during DNA replication initiation.
Guarino Almeida E et al.
Nucleic Acids Research, 2020
CEP41-mediated ciliary tubulin glutamylation drives angiogenesis through AURKA-dependent deciliation.
Ki SM et al.
Embo Reports, 2020
PLK1 targets CtIP to promote microhomology-mediated end joining.
Wang H et al.
Nucleic Acids Research, 2018
Phosphorylation-Induced Motor Shedding Is Required at Mitosis for Proper Distribution and Passive Inheritance of Mitochondria.
Chung JY et al.
Cell Reports, 2016
Opposing roles for JNK and Aurora A in regulating the association of WDR62 with spindle microtubules.
Lim NR et al.
Journal of Cell Science, 2015
INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability.
Plotnikova OV et al.
Journal of Cell Science, 2015
Aurora-A kinase-inactive mutants disrupt the interaction with Ajuba and cause defects in mitotic spindle formation and G2/M phase arrest in HeLa cells.
Bai M et al.
Bmb Reports, 2014
Two newly identified sites in the N-terminal regulatory domain of Aurora-A are essential for auto-inhibition.
Bai M et al.
Biotechnology Letters, 2014
Insights into wild-type and mutant p53 functions provided by genetically engineered mice.
Donehower LA
Human Mutation, 2014
A novel Aurora-A-mediated phosphorylation of p53 inhibits its interaction with MDM2.
Hsueh KW et al.
Biochimica Et Biophysica Acta, 2013
Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.
Tsunematsu T et al.
Nature Communications, 2013
KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.
Xiao L et al.
The Journal of Biological Chemistry, 2011
Rapid calcium-dependent activation of Aurora-A kinase.
Plotnikova OV et al.
Nature Communications, 2010
Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity.
Song SJ et al.
Cancer Research, 2009
Aurora-A kinase phosphorylation of Aurora-A kinase interacting protein (AIP) and stabilization of the enzyme-substrate complex.
Katayama H et al.
Journal of Cellular Biochemistry, 2007
Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.
Katayama H et al.
Nature Genetics, 2004
Human TPX2 is required for targeting Aurora-A kinase to the spindle.
Kufer TA et al.
The Journal of Cell Biology, 2002