Varaico: Literature-Extracted Genetic Variants

Gene:AXIN1
Variant:p.R712*
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AXIN1

NM_003502.4:p.R712*

Associated Papers

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling.

Zhang R et al.

Cancer Research, 2024

38359148 (PubMed )
Supplement: can-23-2268_supplementary_table_7_suppst7.xlsx › HCC-mutations

Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines.

Zhang R et al.

Plos One, 2024

Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.

Wang W et al.

Scientific Reports, 2021

Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes.

Liu P et al.

Gastroenterology, 2020

Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.

Wang W et al.

Neoplasia (new York, N.y.), 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."