Varaico: Literature-Extracted Genetic Variants

Gene:AXIN1
Variant:p.L396M
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AXIN1

NM_003502.4:p.L396M

Associated Papers

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling.

Zhang R et al.

Cancer Research, 2024

miR-155 Is Downregulated in Familial Adenomatous Polyposis and Modulates WNT Signaling by Targeting AXIN1 and TCF4.

Prossomariti A et al.

Molecular Cancer Research : Mcr, 2018

Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of β-Catenin Signaling.

Wang W et al.

Neoplasia (new York, N.y.), 2016

AXIN1 and AXIN2 variants in gastrointestinal cancers.

Mazzoni SM et al.

Cancer Letters, 2014

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling.

Guo X et al.

Genes & Development, 2008

Colorectal cancer and genetic alterations in the Wnt pathway.

Segditsas S et al.

Oncogene, 2006

Sequence variants of the axin gene in breast, colon, and other cancers: an analysis of mutations that interfere with GSK3 binding.

Webster MT et al.

Genes, Chromosomes & Cancer, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."