Varaico: Literature-Extracted Genetic Variants

Gene:AXIN1
Variant:p.G233D
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AXIN1

NM_003502.4:p.G233D

Associated Papers

Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling.

Venhuizen AJ et al.

Iscience, 2026

41550750 (PubMed )
Supplement: mmc1.pdf

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling.

Zhang R et al.

Cancer Research, 2024

38359148 (PubMed )
Supplement: can-23-2268_supplementary_table_7_suppst7.xlsx › CRC-Mutations_

Oncogenic Serine 45-Deleted β-Catenin Remains Susceptible to Wnt Stimulation and APC Regulation in Human Colonocytes.

Parker TW et al.

Cancers, 2020

32751567 (PubMed )
Supplement: cancers-12-02114-s001.zip › cancers-848197_Supplementary_Data_Files_Parker_Rudeen_Neufeld_11july20.xlsx › Axin1_Mutations

Mutational signatures reveal the dynamic interplay of risk factors and cellular processes during liver tumorigenesis.

Letouzé E et al.

Nature Communications, 2017

29101368 (PubMed )
Supplement: 41467_2017_1358_MOESM5_ESM.pdf

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.

Schulze K et al.

Nature Genetics, 2015

25822088 (PubMed )
Supplement: NIHMS62359-supplement-Table3.xlsx › SuppTable_3b_CHC892T
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