Varaico: Literature-Extracted Genetic Variants

Gene:AXIN1
Variant:p.L106R
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AXIN1

NM_003502.4:p.L106R

Associated Papers

Hepatocellular carcinoma-linked AXIN1 mutations drive low Wnt/β-catenin activity enabling niche-independent growth and YAP/TAZ signaling.

Venhuizen AJ et al.

Iscience, 2026

Analysis of Tumor-Associated AXIN1 Missense Mutations Identifies Variants That Activate β-Catenin Signaling.

Zhang R et al.

Cancer Research, 2024

Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.

Anvarian Z et al.

Nature Structural & Molecular Biology, 2016

AXIN1 and AXIN2 variants in gastrointestinal cancers.

Mazzoni SM et al.

Cancer Letters, 2014

Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas.

Taniguchi K et al.

Oncogene, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."