Associated Papers
Advances in the cell biology of the trafficking and processing of amyloid precursor protein: impact of familial Alzheimer's disease mutations.
Wang J et al.
The Biochemical Journal, 2024
GGA1 regulates signal-dependent sorting of BACE1 to recycling endosomes, which moderates Aβ production.
Toh WH et al.
Molecular Biology of the Cell, 2018
Dysregulation of protein trafficking in neurodegeneration.
Wang X et al.
Molecular Neurodegeneration, 2014
GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells.
Kosicek M et al.
Biochemical and Biophysical Research Communications, 2014
Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.
Prabhu Y et al.
Molecular Biology of the Cell, 2012
Demonstration of BACE (beta-secretase) phosphorylation and its interaction with GGA1 in cells by fluorescence-lifetime imaging microscopy.
von Arnim CA et al.
Journal of Cell Science, 2004
Memapsin 2 (beta-secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2.
He X et al.
Febs Letters, 2002
Phosphorylation regulates intracellular trafficking of beta-secretase.
Walter J et al.
The Journal of Biological Chemistry, 2001
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