Associated Papers
The Utility of Genome-Wide Association Studies in Inherited Arrhythmias and Cardiomyopathies.
Dababneh S et al.
Genes, 2025
Circulating Cardiovascular Proteomic Associations With Genetics and Disease.
McGurk KA et al.
Circulation. Genomic and Precision Medicine, 2025
Multiple classes of human intracellular Heme-binding proteins with pathology-associated polymorphisms of heme coordinating residues.
Tsiftsoglou SA et al.
Biochimica Et Biophysica Acta. Molecular Basis of Disease, 2025
Large-scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy.
Tadros R et al.
Nature Genetics, 2025
Proteogenomic Profiling of Treatment-Naïve Metastatic Malignant Melanoma.
Kuras M et al.
Cancers, 2025
Genetic landscape of phospholamban cardiomyopathies.
Vafiadaki E et al.
Frontiers in Cell and Developmental Biology, 2025
Genetic mutations in lymphocytic variant of hypereosinophilic syndrome: study of five siblings.
Walkenhorst M et al.
Frontiers in Medicine, 2025
Bidirectional Risk Modulator and Modifier Variant of Dilated and Hypertrophic Cardiomyopathy in BAG3.
Park J et al.
Jama Cardiology, 2024
The Genetic Factors Influencing Cardiomyopathies and Heart Failure across the Allele Frequency Spectrum.
Mukhopadhyay S et al.
Journal of Cardiovascular Translational Research, 2024
Ethnicity, consanguinity, and genetic architecture of hypertrophic cardiomyopathy.
Allouba M et al.
European Heart Journal, 2023
Base-Excision Repair Mutational Signature in Two Sebaceous Carcinomas of the Eyelid.
Sangiorgi E et al.
Genes, 2023
Plasma proteomic associations with genetics and health in the UK Biobank.
Sun BB et al.
Nature, 2023
Functional analysis of a common BAG3 allele associated with protection from heart failure.
Perez-Bermejo JA et al.
Nature Cardiovascular Research, 2023
BAG3: Nature's Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue.
Brenner CM et al.
Cells, 2023
Genetics of BAG3: A Paradigm for Developing Precision Therapies for Dilated Cardiomyopathies.
Qu HQ et al.
Journal of the American Heart Association, 2022
Whole exome sequencing and co-expression analysis identify an SCN1A variant that modifies pathogenicity in a family with genetic epilepsy and febrile seizures plus.
Hammer MF et al.
Epilepsia, 2022
Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.
Yang J et al.
Science Translational Medicine, 2022
Clinical significance of genetic variation in hypertrophic cardiomyopathy: comparison of computational tools to prioritize missense variants.
Barbosa P et al.
Frontiers in Cardiovascular Medicine, 2022
Genetic and Epigenetic Factors of Takotsubo Syndrome: A Systematic Review.
Ferradini V et al.
International Journal of Molecular Sciences, 2021
Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.
Tadros R et al.
Nature Genetics, 2021
A genetic association study of heart failure: more evidence for the role of BAG3 in idiopathic dilated cardiomyopathy.
de Denus S et al.
Esc Heart Failure, 2020
The Egyptian Collaborative Cardiac Genomics (ECCO-GEN) Project: defining a healthy volunteer cohort.
Aguib Y et al.
Npj Genomic Medicine, 2020
Sequence variants with large effects on cardiac electrophysiology and disease.
Norland K et al.
Nature Communications, 2019
Global view of the RAF-MEK-ERK module and its immediate downstream effectors.
Santini CC et al.
Scientific Reports, 2019
An enhanced workflow for variant interpretation in UniProtKB/Swiss-Prot improves consistency and reuse in ClinVar.
Famiglietti ML et al.
Database : the Journal of Biological Databases and Curation, 2019
Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals.
Myers VD et al.
Jama Cardiology, 2018
Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy.
Esslinger U et al.
Plos One, 2017
A novel miR-371a-5p-mediated pathway, leading to BAG3 upregulation in cardiomyocytes in response to epinephrine, is lost in Takotsubo cardiomyopathy.
d'Avenia M et al.
Cell Death & Disease, 2015
BAG3: a new player in the heart failure paradigm.
Knezevic T et al.
Heart Failure Reviews, 2015
Novel linkage of LMNA Single Nucleotide Polymorphism with Dilated Cardiomyopathy in an Indian case study.
Banerjee A et al.
International Journal of Cardiology. Heart & Vasculature, 2015
The eSNV-detect: a computational system to identify expressed single nucleotide variants from transcriptome sequencing data.
Tang X et al.
Nucleic Acids Research, 2014
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy.
Feldman AM et al.
Journal of Cellular Physiology, 2014
Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.
Friedrich C et al.
Embo Molecular Medicine, 2014
Genetic profiling for risk reduction in human cardiovascular disease.
Puckelwartz MJ et al.
Genes, 2014
Polymorphisms of the antiapoptotic protein bag3 may play a role in the pathogenesis of tako-tsubo cardiomyopathy.
Citro R et al.
International Journal of Cardiology, 2013
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.
Villard E et al.
European Heart Journal, 2011
Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets.
Isokpehi RD et al.
Bioinformatics and Biology Insights, 2010