Varaico: Literature-Extracted Genetic Variants

Gene:BARD1
Variant:p.Q237*
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BARD1

NM_000465.4:p.Q237*

Associated Papers

RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling.

Yao Z et al.

Nature Medicine, 2019

30559419 (PubMed )
Supplement: NIHMS1509287-supplement-2.pdf

Germline Pathogenic Variants in Homologous Recombination and DNA Repair Genes in an Asian Cohort of Young-Onset Colorectal Cancer.

Toh MR et al.

Jnci Cancer Spectrum, 2018

31360874 (PubMed )
Supplement: pky054_supp.docx

Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.

Yao Z et al.

Nature, 2017

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