Varaico: Literature-Extracted Genetic Variants

Gene:BCL10
Variant:p.R58Q
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BCL10

NM_003921.5:p.R58Q

Associated Papers

Bruton's tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.

Coughlin CA et al.

Blood Cancer Journal, 2025

Intravascular Large B-Cell Lymphoma Genomic Profile Is Characterized by Alterations in Genes Regulating NF-κB and Immune Checkpoints.

Gonzalez-Farre B et al.

The American Journal of Surgical Pathology, 2023

36221796 (PubMed )
Supplement: pas-47-202-s007.xlsx › Suppl_Table_4

BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL.

Xia M et al.

Cancer Discovery, 2022

BCL10 Mutants: Architects of Oncogenic Signaling Provide a Blueprint for Precision Medicine.

Phelan JD et al.

Cancer Discovery, 2022

A nucleation barrier spring-loads the CBM signalosome for binary activation.

Rodriguez Gama A et al.

Elife, 2022

35727133 (PubMed )
Supplement: elife-79826-supp1.xlsx › Table_S1

Diffuse large B-cell lymphomas in adults with aberrant coexpression of CD10, BCL6, and MUM1 are enriched in IRF4 rearrangements.

Frauenfeld L et al.

Blood Advances, 2022

34654055 (PubMed )
Supplement: advancesADV2021006034-suppl1.pdf

Lysine acetylation regulates the interaction between proteins and membranes.

Okada AK et al.

Nature Communications, 2021

34753925 (PubMed )
Supplement: 41467_2021_26657_MOESM4_ESM.zip › Bioinformatics.zip › Datasets › Unused › PTMVAR_download.xlsx › Humsavar_overlap_2PSP_PTM5-14-1

The Genetic Landscape of Ocular Adnexa MALT Lymphoma Reveals Frequent Aberrations in NFAT and MEF2B Signaling Pathways.

Magistri M et al.

Cancer Research Communications, 2021

35528192 (PubMed )
Supplement: crc-21-0022-s05.xlsx › Fig3_pathway_variants

Genetic mechanisms of HLA-I loss and immune escape in diffuse large B cell lymphoma.

Fangazio M et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

34050029 (PubMed )
Supplement: pnas.2104504118.sd02.xlsx › Table_S2

Clonal evolution in diffuse large B-cell lymphoma with central nervous system recurrence.

Magnes T et al.

Esmo Open, 2021

33399078 (PubMed )
Supplement: mmc1.pdf

Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma.

Pedrosa L et al.

Scientific Reports, 2021

33479306 (PubMed )
Supplement: 41598_2020_80376_MOESM1_ESM.xlsx › Table_S2._Mutational_data

Novel bioinformatic classification system for genetic signatures identification in diffuse large B-cell lymphoma.

Zhang W et al.

Bmc Cancer, 2020

32736575 (PubMed )
Supplement: 12885_2020_7198_MOESM5_ESM.xlsx › Table_S3

Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma.

Bouska A et al.

Leukemia, 2017

Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.

Ryu GM et al.

Nucleic Acids Research, 2009

19139070 (PubMed )
Supplement: gkn1008_nar-01723-s-2008-File009.xls › TypeIII
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."