Varaico: Literature-Extracted Genetic Variants

Gene:BCL10
Variant:p.L41Q
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BCL10

NM_003921.5:p.L41Q

Associated Papers

Neuroepithelial transforming gene 1 (Net1) binds to caspase activation and recruitment domain (CARD)- and membrane-associated guanylate kinase-like domain-containing (CARMA) proteins and regulates nuclear factor κB activation.

Vessichelli M et al.

The Journal of Biological Chemistry, 2012

Alternative splicing of CARMA2/CARD14 transcripts generates protein variants with differential effect on NF-κB activation and endoplasmic reticulum stress-induced cell death.

Scudiero I et al.

Journal of Cellular Physiology, 2011

Specific effects of BCL10 Serine mutations on phosphorylations in canonical and noncanonical pathways of NF-κB activation following carrageenan.

Bhattacharyya S et al.

American Journal of Physiology. Gastrointestinal and Liver Physiology, 2011

The IRAK-1-BCL10-MALT1-TRAF6-TAK1 cascade mediates signaling to NF-kappaB from Toll-like receptor 4.

Dong W et al.

The Journal of Biological Chemistry, 2006

Essential role for IkappaB kinase beta in remodeling Carma1-Bcl10-Malt1 complexes upon T cell activation.

Wegener E et al.

Molecular Cell, 2006

CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10.

Koseki T et al.

The Journal of Biological Chemistry, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."