Varaico: Literature-Extracted Genetic Variants

Gene:BCL11A
Variant:p.R68W
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BCL11A

NM_022893.4:p.R68W

Associated Papers

Evaluating Immune Checkpoint Blockade in Metastatic Castration-Resistant Prostate Cancers with Deleterious CDK12 Alterations in the Phase 2 IMPACT Trial.

Nguyen CB et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024

Precision Editing as a Therapeutic Approach for β-Hemoglobinopathies.

Paschoudi K et al.

International Journal of Molecular Sciences, 2023

Manipulation of Developmental Gamma-Globin Gene Expression: an Approach for Healing Hemoglobinopathies.

Venkatesan V et al.

Molecular and Cellular Biology, 2020

Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.

Martyn GE et al.

Nature Genetics, 2018

The relevance of hemoglobin F measurement in the diagnosis of thalassemias and related hemoglobinopathies.

Mosca A et al.

Clinical Biochemistry, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."