Associated Papers
Docking-based approach for identification of mutations that disrupt binding between Bcl-2 and Bax proteins: Inducing apoptosis in cancer cells.
Raghav PK et al.
Molecular Genetics & Genomic Medicine, 2019
Characterization of a novel venetoclax resistance mutation (BCL2 Phe104Ile) observed in follicular lymphoma.
Blombery P et al.
British Journal of Haematology, 2019
Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations.
Birkinshaw RW et al.
Nature Communications, 2019
Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia.
Blombery P et al.
Cancer Discovery, 2019
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