Varaico: Literature-Extracted Genetic Variants

Gene:BCL2
Variant:p.T56A
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BCL2

NM_000633.3:p.T56A

Associated Papers

Oncogenic Mutations in the DNA-Binding Domain of FOXO1 that Disrupt Folding: Quantitative Insights from Experiments and Molecular Simulations.

Novack D et al.

Biochemistry, 2022

Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2.

Sangree AK et al.

Nature Communications, 2022

35288574 (PubMed )
Supplement: 41467_2022_28884_MOESM11_ESM.xlsx › NG-ABE_Library_Annotation

NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1.

Shrestha BK et al.

The Journal of Biological Chemistry, 2020

Mitochondrial dysfunction in Parkinson's disease.

Bose A et al.

Journal of Neurochemistry, 2016

Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy.

Su YC et al.

Biochimica Et Biophysica Acta, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."