Associated Papers
Patient tissue-derived FGFR4-variant and wild-type colorectal cancer organoid development and anticancer drug sensitivity testing.
Lin H et al.
Heliyon, 2024
Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort.
Vanni I et al.
Journal of Translational Medicine, 2024
Integrative genomic analyses combined with molecular dynamics simulations reveal the impact of deleterious mutations of Bcl-2 gene on the apoptotic machinery and implications in carcinogenesis.
Elamin G et al.
Frontiers in Genetics, 2024
Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies.
Kleo K et al.
Journal of Cancer Research and Clinical Oncology, 2023
Application of circulating tumour DNA in terms of prognosis prediction in Chinese follicular lymphoma patients.
Zhao M et al.
Frontiers in Genetics, 2023
Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2.
Sangree AK et al.
Nature Communications, 2022
Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses.
Kim SC et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2022
Association of BCL2 polymorphisms and the IL19 single nucleotide polymorphism rs2243188 with systemic lupus erythematosus.
Wang W et al.
The Journal of International Medical Research, 2021
Stemness regulation of the adrenal mixed corticomedullary tumorigenesis-a case-control study.
Chiou HC et al.
Neoplasia (new York, N.y.), 2020
Cumulative Evidence for Associations between Genetic Variants and Risk of Esophageal Cancer.
Li G et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2020
Impact of lymphoma-linked Asn11Tyr point mutation on the interaction between Bcl-2 and a BH3 mimetic: Insights from molecular dynamics simulation.
Singh K et al.
Chemical Biology & Drug Design, 2020
Mutations in apoptotic genes and micronucleus occurrence in vinyl chloride-exposed workers in China.
Feng N et al.
Environmental and Molecular Mutagenesis, 2017
Association of single nucleotide polymorphisms in the coding region of Bcl-2 with the occurrence and prognosis of colorectal cancer: A case-control study.
Huang B et al.
Cancer Biomarkers : Section a of Disease Markers, 2017
The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas.
Lim CH et al.
Oncotarget, 2016
Quantitative assessment of the association between Fas/FasL gene polymorphism and susceptibility to esophageal carcinoma in a north Chinese population.
Zhang M et al.
Cancer Medicine, 2016
P53 rs1042522 and CD95 rs1800682 genetic variations in HCV-4a response to antiviral therapy.
Abd-Rabou AA et al.
Genes & Diseases, 2015
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.
Correia C et al.
Blood, 2015
Role of polymorphisms in BCL-2 and BAX genes in modulating the risk of developing non-Hodgkin lymphoma.
Wang WL et al.
Leukemia & Lymphoma, 2014
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.
Wang J et al.
Plos One, 2014
The -938A/A genotype of BCL2 gene is associated with esophageal cancer.
Liu Z et al.
Medical Oncology (northwood, London, England), 2012
Does HCV Patients Who Have BCL2 43Ala Genotype and Normal GH1 Levels Can Achieve Response to IFN Based Therapy?
Eskander EF et al.
Indian Journal of Clinical Biochemistry : Ijcb, 2012
Genetic variation in BCL-2 and response to interferon in hepatitis C virus type 4 patients.
Shaker OG et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 2011
BCL2 Ala43Thr is a functional variant associated with protection against azoospermia in a Han-Chinese population.
Ma J et al.
Biology of Reproduction, 2010
BCL2 gene polymorphism could predict the treatment outcomes in acute myeloid leukemia patients.
Moon JH et al.
Leukemia Research, 2010
A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.
Young RP et al.
Postgraduate Medical Journal, 2009
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.
Ryu GM et al.
Nucleic Acids Research, 2009
Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis.
Pabalan N et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2008
Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer.
Jain M et al.
Cancer Biology & Therapy, 2007
Role of BCL2 (ala43thr), CCND1 (G870A) and FAS (A-670G) polymorphisms in modulating the risk of developing esophageal cancer.
Jain M et al.
Cancer Detection and Prevention, 2007
Identification of variants in cyclin D1 ( CCND1) and B-Cell CLL/lymphoma 2 ( BCL2).
Park BL et al.
Journal of Human Genetics, 2004
No evidence of a functionally significant polymorphism of the BCL2 gene in Danish, Finnish and Basque type 1 diabetes families.
Heding PE et al.
Genes and Immunity, 2001
The polymorphic 43Thr bcl-2 protein confers relative resistance to autoimmunity: an analytical evaluation.
Komaki S et al.
Human Genetics, 1998