Varaico: Literature-Extracted Genetic Variants

Gene:BCR
Variant:p.S315F
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BCR

NM_004327.4:p.S315F

Associated Papers

Innovative rapid screening for complex BCR-ABL1 kinase domain mutations in TKI-treated leukaemia patients.

Lan Y et al.

British Journal of Cancer, 2025

40588514 (PubMed )
Supplement: 41416_2025_3098_MOESM1_ESM.pdf

Comprehensive analysis of tyrosine kinase domain mutations and imatinib resistance in chronic myeloid leukemia patients.

Dhangar S et al.

Leukemia Research, 2025

Detection of ABL1 kinase domain mutations in therapy-naïve BCR-ABL1-positive acute lymphoblastic leukemia.

Baer C et al.

Haematologica, 2022

34758608 (PubMed )
Supplement: 2021_279807_BAER_SUPPL.pdf

ABL1 tyrosine kinase domain mutations in chronic myeloid leukemia treatment resistance.

Vacarean-Trandafir IC et al.

Molecular Biology Reports, 2019

Outcomes of 219 chronic myeloid leukaemia patients with additional chromosomal abnormalities and/or tyrosine kinase domain mutations.

Xue M et al.

International Journal of Laboratory Hematology, 2019

Rapid identification of compound mutations in patients with Philadelphia-positive leukaemias by long-range next generation sequencing.

Kastner R et al.

European Journal of Cancer (oxford, England : 1990), 2014

Sensitive detection of BCR-ABL1 mutations in patients with chronic myeloid leukemia after imatinib resistance is predictive of outcome during subsequent therapy.

Parker WT et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2011

Mutations in ABL kinase domain are associated with inferior progression-free survival.

Sharma P et al.

Leukemia & Lymphoma, 2010

Heterogeneity in detecting Abl kinase mutations and better sensitivity using circulating plasma RNA.

Ma W et al.

Leukemia, 2006

High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance.

Branford S et al.

Blood, 2002

Two different point mutations in ABL gene ATP-binding domain conferring Primary Imatinib resistance in a Chronic Myeloid Leukemia (CML) patient: A case report.

Iqbal Z et al.

Biological Procedures Online, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."