Associated Papers
Accurate affinity models for SH2 domains from peptide binding assays and free-energy regression.
Gagoski D et al.
Protein Science : a Publication of the Protein Society, 2025
Accurate sequence-to-affinity models for SH2 domains from multi-round peptide binding assays coupled with free-energy regression.
Gagoski D et al.
Biorxiv : the Preprint Server for Biology, 2025
BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation.
Picas L et al.
Communications Biology, 2024
Coding variants identified in patients with diabetes alter PICK1 BAR domain function in insulin granule biogenesis.
Andersen RC et al.
The Journal of Clinical Investigation, 2022
Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton.
D'Alessandro M et al.
Developmental Cell, 2015
Adult-onset autosomal dominant centronuclear myopathy due to BIN1 mutations.
Böhm J et al.
Brain : a Journal of Neurology, 2014
N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy.
Falcone S et al.
Embo Molecular Medicine, 2014
Amphiphysin 2 (BIN1) in physiology and diseases.
Prokic I et al.
Journal of Molecular Medicine (berlin, Germany), 2014
Mutations in BIN1 associated with centronuclear myopathy disrupt membrane remodeling by affecting protein density and oligomerization.
Wu T et al.
Plos One, 2014
The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies.
Royer B et al.
Embo Reports, 2013
Altered splicing of the BIN1 muscle-specific exon in humans and dogs with highly progressive centronuclear myopathy.
Böhm J et al.
Plos Genetics, 2013
Clinical utility gene card for: Centronuclear and myotubular myopathies.
Biancalana V et al.
European Journal of Human Genetics : Ejhg, 2012
Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies.
Toussaint A et al.
Acta Neuropathologica, 2011
Case report of intrafamilial variability in autosomal recessive centronuclear myopathy associated to a novel BIN1 stop mutation.
Böhm J et al.
Orphanet Journal of Rare Diseases, 2010
Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy.
Nicot AS et al.
Nature Genetics, 2007
Mutant BIN1-Dynamin 2 complexes dysregulate membrane remodeling in the pathogenesis of centronuclear myopathy.
Fujise K et al.
The Journal of Biological Chemistry, 0